Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia associated with gout. It reduces serum uric acid concentration through the inhibition of URAT1, an enzyme responsible for reuptake of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with diuretic-induced hyperuricemi...
适用与一种黄嘌呤氧化酶抑制剂(别嘌醇、苯溴马隆、非布司他等)联用为与痛风关联高尿酸血症的治疗。一般不单药使用。
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.