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Delafloxacin

Generic Name
Delafloxacin
Brand Names
Baxdela, Quofenix
Drug Type
Small Molecule
Chemical Formula
C18H12ClF3N4O4
CAS Number
189279-58-1
Unique Ingredient Identifier
6315412YVF

Overview

Delafloxacin is a fluoroquinolone antibiotic which has been used in trials studying the treatment and basic science of Gonorrhea, Hepatic Impairment, Bacterial Skin Diseases, Skin Structure Infections, and Community Acquired Pneumonia, among others. It was approved in June 2017 under the trade name Baxdela for use in the treatment of acute bacterial skin and skin structure infections.

Background

Delafloxacin is a fluoroquinolone antibiotic which has been used in trials studying the treatment and basic science of Gonorrhea, Hepatic Impairment, Bacterial Skin Diseases, Skin Structure Infections, and Community Acquired Pneumonia, among others. It was approved in June 2017 under the trade name Baxdela for use in the treatment of acute bacterial skin and skin structure infections.

Indication

Delafloxacin is indicated for the treatment of acute bacterial skin and skin structure infections caused by the Gram-positive organisms Staphylococcus aureus (including methicillin-resistant and methicillin-susceptible isolates), Staphylococcus haemolyticus, Staphylococcus lugdunensis, Streptococcus agalactiae, Streptococcus anginosus Group (including Streptococcus anginosus, Streptococcus intermedius, and Streptococcus constellatus), Streptococcus pyogenes, and Enterococcus faecalis as well as the Gram-negative organisms Escherichia coli, Enterobacter cloacae, Klebsiella pneumoniae, and Pseudomonas aeruginosa .

Associated Conditions

  • Acute Bacterial Skin and Skin Structure Infection (ABSSSI)
  • Community-Acquired Bacterial Pneumonia (CABP)

FDA Approved Products

Baxdela
Manufacturer:Melinta Therapeutics, LLC
Route:INTRAVENOUS
Strength:300 mg in 10.5 mL
Approved: 2021/07/02
NDC:70842-102
Baxdela
Manufacturer:Melinta Therapeutics, LLC
Route:ORAL
Strength:450 mg in 1 1
Approved: 2021/07/02
NDC:70842-101

Singapore Approved Products

No Singapore products found for this drug

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