Overview
Mivacurium is a bisbenzylisoquinolinium based neuromuscular blocker or muscle relaxant. It binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a block of neuromuscular transmission.
Background
Mivacurium is a bisbenzylisoquinolinium based neuromuscular blocker or muscle relaxant. It binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a block of neuromuscular transmission.
Indication
For inpatients and outpatients, as an adjunct to general anesthesia, to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
Associated Conditions
No associated conditions information available.
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2024/11/29 | Not Applicable | Not yet recruiting | Peng Liang | ||
2022/09/28 | N/A | Completed | Matias Vested | ||
2016/09/26 | N/A | Completed | Jakob Louis Thomsen | ||
2015/06/16 | Phase 2 | UNKNOWN | Tang-Du Hospital | ||
2014/04/21 | Phase 4 | Completed | |||
2013/10/21 | Not Applicable | Completed | Dr. Horst Schmidt Klinik GmbH | ||
2013/07/24 | Phase 1 | Completed |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| No FDA approvals found for this drug. | |||||
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| MIVACRON INJECTION 10 mg/5 ml | SIN07624P | INJECTION | 10 mg/5 ml | 1/26/1994 |
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| Mivacurium Chloride Injection | 国药准字H20249405 | 化学药品 | 注射剂 | 11/15/2024 | |
| Mivacurium Chloride Injection | 国药准字H20249404 | 化学药品 | 注射剂 | 11/15/2024 | |
| Mivacurium Chloride Injection | 国药准字HJ20181156 | 化学药品 | 注射剂 | 1/6/2025 | |
| Mivacurium Chloride Injection | 国药准字HJ20181155 | 化学药品 | 注射剂 | 1/6/2025 | |
| Mivacurium Chloride Injection | 国药准字H20213230 | 化学药品 | 注射剂 | 3/30/2021 | |
| Mivacurium Chloride Injection | 国药准字H20213231 | 化学药品 | 注射剂 | 3/30/2021 | |
| Mivacurium Chloride Injection | H20181155 | 化学药品 | 注射剂 | 6/10/2020 | |
| Mivacurium Chloride Injection | H20181156 | 化学药品 | 注射剂 | 6/10/2020 |
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| MIVACRON INJ 0.2% | N/A | N/A | N/A | 7/14/1994 |
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| MIVACRON mivacurium 10mg/5mL injection | 42972 | Medicine | A | 5/16/1994 | |
| MIVACRON mivacurium 50mg/25mL injection | 42946 | Medicine | A | 5/25/1994 | |
| MIVACRON mivacurium 20mg/10mL injection | 42947 | Medicine | A | 5/16/1994 |