Mivacurium

Overview

Mivacurium is a bisbenzylisoquinolinium based neuromuscular blocker or muscle relaxant. It binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a block of neuromuscular transmission.

Indication

For inpatients and outpatients, as an adjunct to general anesthesia, to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.

Associated Conditions

No associated conditions information available.

Clinical Trials

Title	Posted	Study ID	Phase	Status	Sponsor
Muscle Relaxant Effect and Safety of Mivacurium Chloride and Succinylcholine for Bronchoscopy	2024/11/29	NCT06709066	Not Applicable	Not yet recruiting	Peng Liang
Mivacurium 0.2 mg/kg in Young (18 - 40 Years) and Elderly (= 80 Years) Patients	2022/09/28	NCT05558137	N/A	Completed	Matias Vested
Use of Neuromuscular Blocking Agents and Neuromuscular Monitoring in 7 Danish Teaching Hospitals	2016/09/26	NCT02914119	N/A	Completed	Jakob Louis Thomsen
Mivacurium Chloramine Muscle Relaxation Effect in Patients With Liver Cirrhosis	2015/06/16	NCT02473601	Phase 2	UNKNOWN	Tang-Du Hospital
A Prospective, Multi-center, Randomized Controlled Study of Muscle Relaxation Effect and Safety of Mivacurium Chloride in Pediatric Surgery Patients	2014/04/21	NCT02117401	Phase 4	Completed	Jiangsu Nhwa Pharmaceutical Co., Ltd.
Low Dose Mivacurium vs. Low Dose Succinylcholine for Rigid Bronchoscopy	2013/10/21	NCT01966484	Not Applicable	Completed	Dr. Horst Schmidt Klinik GmbH
Sex-related Differences in the Response to the Muscle Relaxant Drug Mivacurium	2013/07/24	NCT01906528	Phase 1	Completed	University of California, San Francisco

FDA Drug Approvals

Approved Product	Manufacturer	NDC Code	Route	Strength	Effective Date
No FDA approvals found for this drug.

EMA Drug Approvals

Approved Product	Authorization Holder	Status	Issued Date
No EMA approvals found for this drug.

HSA Drug Approvals

Approved Product	Manufacturer	Approval Number	Dosage Form	Strength	Approval Date
MIVACRON INJECTION 10 mg/5 ml	GLAXOSMITHKLINE MANUFACTURING SPA, Aspen SVP	SIN07624P	INJECTION	10 mg/5 ml	1/26/1994

NMPA Drug Approvals

Approved Product	Company	Approval Number	Drug Type	Dosage Form	Approval Date
No NMPA approvals found for this drug.

PPB Drug Approvals

Approved Product	Registration No.	Company	Licence No.	Strength	Registration Date
MIVACRON INJ 0.2%	N/A	Aspen Pharmacare Asia Limited	N/A	N/A	7/14/1994

TGA Drug Approvals

Approved Product	ARTG ID	Sponsor	Registration Type	Status	Registration Date
MIVACRON mivacurium 10mg/5mL injection	42972	Aspen Pharmacare Australia Pty Ltd	Medicine	A	5/16/1994
MIVACRON mivacurium 50mg/25mL injection	42946	Aspen Pharmacare Australia Pty Ltd	Medicine	A	5/25/1994
MIVACRON mivacurium 20mg/10mL injection	42947	Aspen Pharmacare Australia Pty Ltd	Medicine	A	5/16/1994

Health Canada Drug Approvals

Approved Product	Company	DIN	Dosage Form	Strength	Market Date
No Health Canada approvals found for this drug.

CIMA AEMPS Drug Approvals

Approved Product	Company	Registration Number	Pharmaceutical Form	Prescription Type	Status
No CIMA AEMPS (Spain) approvals found for this drug.

Philippines FDA Drug Approvals

Approved Product	Company	License Number	Dosage Form	Strength	Approval Date
No Philippines FDA approvals found for this drug.

Saudi SFDA Drug Approvals

Approved Product	Company	License Number	Dosage Form	Strength	Approval Date
No Saudi SFDA approvals found for this drug.

Malaysia NPRA Drug Approvals

Approved Product	Company	Registration Number	Dosage Form	Strength	Approval Date
No Malaysia NPRA approvals found for this drug.

UK EMC Drug Information

Medicine Name	MA Holder	MA Number	Pharmaceutical Form	Active Ingredient	Authorization Date
No UK EMC drug information found for this drug.

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