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Pacira BioSciences has reached a settlement agreement with Fresenius, Jiangsu Hengrui Pharmaceuticals, and eVenus Pharmaceuticals regarding patents for its pain management drug Exparel, protecting market exclusivity until 2030.
Edgewise Therapeutics' novel cardiac sarcomere modulator EDG-7500 demonstrated significant reductions in left ventricular outflow tract gradient in obstructive HCM patients without meaningful changes in ejection fraction.
Edgewise Therapeutics is prioritizing the completion of recruitment for the GRAND CANYON trial for Becker muscular dystrophy in early 2025.
Edgewise Therapeutics is advancing EDG-7500 for HCM, with a readout expected in September, showing potential to reduce titration needs.
Data from over 5,500 patients in the REMS program showed a low incidence of ejection fraction drop (4.6%) and heart failure hospitalization (1%).