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Amibegron is an agonist for atypical beta3-adrenoceptors which inhibits intestinal motility.
Amibegron is an agonist for atypical beta3-adrenoceptors which inhibits intestinal motility.
SR 58611 has positive chronotropic effect which is mainly of peripheral origin and can be attributed to a baroreceptor-mediated reflex due to the beta3-adrenoceptor mediated vasodilation with an increase in sympathetic tone and a reduction in vagal tone to the heart.
Investigated for use/treatment in depression, irritable bowel syndrome (IBS), and obesity.
每项发明一条，涵盖美国、欧洲、PCT 与中国的同族专利。
