Etacrynic acid

Generic Name
Etacrynic acid
Brand Names
Edecrin
Drug Type
Small Molecule
Chemical Formula
C13H12Cl2O4
CAS Number
58-54-8
Unique Ingredient Identifier
M5DP350VZV
Background

A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.

Indication

For the treatment of high blood pressure and edema caused by diseases like congestive heart failure, liver failure, and kidney failure.

Associated Conditions
Ascites, Congenital Heart Disease (CHD), Edema, Nephrotic Syndrome
Associated Therapies
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