Levocarnitine

Generic Name
Levocarnitine
Brand Names
Carnitor
Drug Type
Small Molecule
Chemical Formula
C7H15NO3
CAS Number
541-15-1
Unique Ingredient Identifier
0G389FZZ9M
Background

Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.

Indication

⑴用于继发性肉碱缺乏症。主要用于慢性肾衰长期血透患者因肉碱缺乏产生的一系列并发症状,临床表现如心肌病、骨骼肌病、心律失常、高脂血症,以及低血压和透析中肌痉挛等。

⑵用于罕见病β-酮硫解酶缺乏症(BKD)和原发性肉碱缺乏症(PCD)。

⑶用于罕见病戊二酸Ⅰ型。

⑷用于维持罕见病同型半胱氨酸血症引起的血液游离肉碱的正常水平。

Associated Conditions
Carnitine Deficiency, Congenital carnitine deficiency, Secondary Carnitine deficiency
Associated Therapies
-

Effect of the Administration of L-Carnitine on Body Weight in Women in Crossfit Training

First Posted Date
2018-02-19
Last Posted Date
2018-02-20
Lead Sponsor
University of Guadalajara
Target Recruit Count
24
Registration Number
NCT03436277
Locations
🇲🇽

Centro Universitario de Tonalá, Tonalá, Jalisco, Mexico

L-carnitine vs Placebo for the Treatment of Muscle Cramps After Imatinib in Gastrointestinal Stromal Tumors

First Posted Date
2018-02-08
Last Posted Date
2020-07-13
Lead Sponsor
Asan Medical Center
Target Recruit Count
4
Registration Number
NCT03426722
Locations
🇰🇷

Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea, Republic of

Effect of Levocarnitine Supplementation for the Management of Fatigue in Levothyroxine-Treated Hypothyroid Patients

Not Applicable
Conditions
Interventions
First Posted Date
2017-12-14
Last Posted Date
2017-12-26
Lead Sponsor
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Target Recruit Count
90
Registration Number
NCT03372772
Locations
🇧🇩

Phamacology Department, BSMMU, Dhaka, Shahbag, Bangladesh

N-Acetylcysteine and L-carnitine in Pcos

Phase 2
Completed
Conditions
Interventions
First Posted Date
2017-05-23
Last Posted Date
2018-09-18
Lead Sponsor
Zagazig University
Target Recruit Count
164
Registration Number
NCT03164421
Locations
🇪🇬

Zagazig University, Zagazig, Egypt

L-carnitine Corrects Ammonia Metabolism in Hepatectomized Patients

First Posted Date
2017-01-16
Last Posted Date
2017-01-16
Lead Sponsor
Kochi University
Target Recruit Count
80
Registration Number
NCT03021876
Locations
🇯🇵

Kochi Health Sciences Center, Kochi, Japan

Carnitine Infusion and Insulin Resistance

First Posted Date
2016-03-30
Last Posted Date
2018-04-26
Lead Sponsor
Maastricht University Medical Center
Target Recruit Count
17
Registration Number
NCT02722902
Locations
🇳🇱

Maastricht University Medical Center, Maastricht, Limburg, Netherlands

L-carnitine on the Prevention of Renal Scarring in Acute Pyelonephritis

Phase 3
Conditions
Interventions
First Posted Date
2013-12-11
Last Posted Date
2013-12-11
Lead Sponsor
Shahid Beheshti University
Target Recruit Count
78
Registration Number
NCT02007889
Locations
🇮🇷

Isfahan University of Medical Sciences,Alzahra Hospital, Isfahan, Iran, Islamic Republic of

Identification of Carnitine-Responsive Cardiomyopathy

Phase 4
Conditions
Interventions
First Posted Date
2013-07-22
Last Posted Date
2013-07-22
Lead Sponsor
University Health Network, Toronto
Target Recruit Count
30
Registration Number
NCT01904396
Locations
🇨🇦

University Health Network, Toronto, Ontario, Canada

Preventing Contrast-induced Nephropathy: Evaluating Hydration Strategies and L-carnitine Administration

First Posted Date
2013-02-08
Last Posted Date
2016-03-22
Lead Sponsor
Centre Hospitalier Universitaire de Nīmes
Target Recruit Count
9
Registration Number
NCT01786824
Locations
🇫🇷

CHU de Nîmes - Hôpital Universitaire Carémeau, Nîmes Cedex 09, Gard, France

🇫🇷

CHU de Montpellier - Hôpital Lapeyronie, Montpellier, France

🇫🇷

CHU d'Angers - Hôtel-Dieu, Angers, France

and more 2 locations

Effect of Early L-Carnitine Supplementation on Neurodevelopmental Outcomes in Very Preterm Infants

First Posted Date
2013-02-04
Last Posted Date
2023-03-08
Lead Sponsor
Montefiore Medical Center
Target Recruit Count
144
Registration Number
NCT01783041
Locations
🇺🇸

Montefiore Medical Center - Wakefield Division, Bronx, New York, United States

🇺🇸

Montefiore Medical Center - Jack D. Weiler Division, Bronx, New York, United States

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