Levocarnitine
- Generic Name
- Levocarnitine
- Brand Names
- Carnitor
- Drug Type
- Small Molecule
- Chemical Formula
- C7H15NO3
- CAS Number
- 541-15-1
- Unique Ingredient Identifier
- 0G389FZZ9M
- Background
Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
- Indication
⑴用于继发性肉碱缺乏症。主要用于慢性肾衰长期血透患者因肉碱缺乏产生的一系列并发症状，临床表现如心肌病、骨骼肌病、心律失常、高脂血症，以及低血压和透析中肌痉挛等。
⑵用于罕见病β-酮硫解酶缺乏症（BKD）和原发性肉碱缺乏症（PCD）。
⑶用于罕见病戊二酸Ⅰ型。
⑷用于维持罕见病同型半胱氨酸血症引起的血液游离肉碱的正常水平。
- Associated Conditions
- Carnitine Deficiency, Congenital carnitine deficiency, Secondary Carnitine deficiency
- Associated Therapies
- -
Safety and Effectiveness of Giving Adefovir (Preveon) Plus Other Anti-HIV Drugs to HIV-Infected Patients Who Have Not Responded to Other Anti-HIV Drug Combinations
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Gilead Sciences
- Registration Number
- NCT00002398
- Locations
- 🇺🇸
Gilead Sciences Inc, Foster City, California, United States
Indinavir Plus Efavirenz Plus Adefovir Dipivoxil in HIV-Infected Patients Who Have Not Had Success With Nelfinavir
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 120
- Registration Number
- NCT00002220
- Locations
- 🇺🇸
Hawaii AIDS Clinical Trial Unit, Honolulu, Hawaii, United States
🇺🇸LAC / USC Med Ctr / Infectious Diseases, Los Angeles, California, United States
🇺🇸Med Ctr of Delaware, Wilmington, Delaware, United States
A Study of Several Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Used Indinavir
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-04
- Target Recruit Count
- 300
- Registration Number
- NCT00000892
- Locations
- 🇺🇸
Cornell Univ Med Ctr, New York, New York, United States
🇺🇸Mount Sinai Med Ctr, New York, New York, United States
🇺🇸Univ of Tennessee / E Tennessee Comprehensive Hemophilia Ctr, Knoxville, Tennessee, United States
A Study on Amprenavir in Combination With Other Anti-HIV Drugs in HIV-Positive Patients
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-10-29
- Target Recruit Count
- 475
- Registration Number
- NCT00000912
- Locations
- 🇺🇸
USC Univ Hosp & Ambulatory Hlth Care Ctr / USC Med Ctr, Los Angeles, California, United States
🇺🇸Emory Univ, Atlanta, Georgia, United States
🇺🇸UCLA CARE Ctr, Los Angeles, California, United States
The Safety and Effectiveness of Adefovir Dipivoxil in the Treatment of HIV-Infected Patients
- Conditions
- Interventions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2013-10-01
- Target Recruit Count
- 505
- Registration Number
- NCT00001082
- Locations
- 🇺🇸
North Jersey Community Research Initiative, Newark, New Jersey, United States
🇺🇸Community Consortium / UCSF, San Francisco, California, United States
🇺🇸Washington Reg AIDS Prog / Dept of Infect Dis, Washington, District of Columbia, United States
The Effectiveness of Nelfinavir and Efavirenz, Used Alone or Together, Combined With Other Anti-HIV Drugs in Patients Who Have Taken Anti-HIV Drugs
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-01
- Target Recruit Count
- 300
- Registration Number
- NCT00001087
- Locations
- 🇺🇸
Rush Univ. Med. Ctr. ACTG CRS, Chicago, Illinois, United States
🇺🇸Cook County Hosp. CORE Ctr., Chicago, Illinois, United States
🇺🇸Johns Hopkins Adult AIDS CRS, Baltimore, Maryland, United States
Drug Development Updates
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