Piperaquine
- Generic Name
- Piperaquine
- Drug Type
- Small Molecule
- Chemical Formula
- C29H32Cl2N6
- CAS Number
- 4085-31-8
- Unique Ingredient Identifier
- A0HV2Q956Y
Overview
Piperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China . Its use declined in the 1980's as piperaquine resistant strains of Plasmodium falciparum appeared and artemisinin derivatives became available. It has come back into use in combination with the artemisinin derivative Artenimol as part of the combination product Eurartesim . Eurartesim was first authorized for market by the European Medicines Agency in October 2011.
Background
Piperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China . Its use declined in the 1980's as piperaquine resistant strains of Plasmodium falciparum appeared and artemisinin derivatives became available. It has come back into use in combination with the artemisinin derivative Artenimol as part of the combination product Eurartesim . Eurartesim was first authorized for market by the European Medicines Agency in October 2011.
Indication
For the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg . Used in combination with Artenimol.
Associated Conditions
- Malaria caused by Plasmodium falciparum
Clinical Trials
FDA Approved Products
Singapore Approved Products
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