MedPath

Urea

Generic Name
Urea
Brand Names
Cem-urea, Umecta, Utopic
Drug Type
Small Molecule
Chemical Formula
CH4N2O
CAS Number
57-13-6
Unique Ingredient Identifier
8W8T17847W

Overview

A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.

Background

A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.

Indication

Urea is used topically for debridement and promotion of normal healing of hyperkeratotic surface lesions, particularly where healing is retarded by local infection, necrotic tissue, fibrinous or purulent debris or eschar. Urea is useful for the treatment of hyperkeratotic conditions such as dry, rough skin, dermatitis, psoriasis, xerosis, ichthyosis, eczema, keratosis, keratoderma, corns and calluses, as well as damaged, devitalized and ingrown nails.

Associated Conditions

  • Allergic Skin Reaction
  • Atopic Dermatitis
  • Contact Dermatitis
  • Dermatitis
  • Dry Eyes
  • Dry Skin
  • Dry Skin; Eczema
  • Eczema, Dyshidrotic
  • Eye pruritus
  • Helicobacter Pylori Infection
  • Insect Bites
  • Lichen Planus (LP)
  • Neurodermatitis
  • Nummular Dermatitis
  • Psoriasis
  • Seborrheic Dermatitis
  • Sunburn
  • Anal eczema
  • Calluses

FDA Approved Products

UREA
Manufacturer:Exact-Rx, Inc.
Route:TOPICAL
Strength:450 mg in 1 g
Approved: 2023/10/23
NDC:42808-202
Urea 40 Percent
Manufacturer:Bryant Ranch Prepack
Route:TOPICAL
Strength:400 mg in 1 g
Approved: 2022/04/18
NDC:63629-9266
UREA
Manufacturer:AvPAK
Route:TOPICAL
Strength:40 g in 100 g
Approved: 2023/02/24
NDC:50268-872
Urea 40 Percent
Manufacturer:Bryant Ranch Prepack
Route:TOPICAL
Strength:400 mg in 1 g
Approved: 2022/04/18
NDC:63629-9267
Urea Cream 41%
Manufacturer:Laser Pharmaceuticals, LLC
Route:TOPICAL
Strength:410 mg in 1 g
Approved: 2023/10/11
NDC:16477-341

Singapore Approved Products

No Singapore products found for this drug

Drug Development Updates

Stay informed with timely notifications on clinical trials and research advancements.

© Copyright 2025. All Rights Reserved by MedPath