MedPath

Urea

Generic Name
Urea
Brand Names
Cem-urea, Umecta, Utopic
Drug Type
Small Molecule
Chemical Formula
CH4N2O
CAS Number
57-13-6
Unique Ingredient Identifier
8W8T17847W

Overview

A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.

Background

A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.

Indication

Urea is used topically for debridement and promotion of normal healing of hyperkeratotic surface lesions, particularly where healing is retarded by local infection, necrotic tissue, fibrinous or purulent debris or eschar. Urea is useful for the treatment of hyperkeratotic conditions such as dry, rough skin, dermatitis, psoriasis, xerosis, ichthyosis, eczema, keratosis, keratoderma, corns and calluses, as well as damaged, devitalized and ingrown nails.

Associated Conditions

  • Allergic Skin Reaction
  • Atopic Dermatitis
  • Contact Dermatitis
  • Dermatitis
  • Dry Eyes
  • Dry Skin
  • Dry Skin; Eczema
  • Eczema, Dyshidrotic
  • Eye pruritus
  • Helicobacter Pylori Infection
  • Insect Bites
  • Lichen Planus (LP)
  • Neurodermatitis
  • Nummular Dermatitis
  • Psoriasis
  • Seborrheic Dermatitis
  • Sunburn
  • Anal eczema
  • Calluses

FDA Approved Products

Urea Cream 41%
Manufacturer:Canton Laboratories
Route:TOPICAL
Strength:410 mg in 1 g
Approved: 2023/10/26
NDC:69437-341
RYNODERM
Manufacturer:SOLUTECH PHARMACEUTICALS LLC
Route:TOPICAL
Strength:375 mg in 1 g
Approved: 2017/10/27
NDC:70350-2626
UREA
Manufacturer:Palmetto Pharmaceuticals Inc.
Route:TOPICAL
Strength:400 mg in 1 g
Approved: 2023/02/24
NDC:68134-801
UREA
Manufacturer:AUSTIN PHARMACEUTICALS, LLC
Route:TOPICAL
Strength:390 mg in 1 g
Approved: 2022/08/25
NDC:42792-101
Urea 40 Percent
Manufacturer:Method Pharmaceuticals, LLC
Route:TOPICAL
Strength:400 mg in 1 g
Approved: 2023/12/12
NDC:58657-487

Singapore Approved Products

No Singapore products found for this drug

Drug Development Updates

Stay informed with timely notifications on clinical trials and research advancements.

© Copyright 2025. All Rights Reserved by MedPath