Tetrofosmin
- Generic Name
- Tetrofosmin
- Drug Type
- Small Molecule
- Chemical Formula
- C18H40O4P2
- CAS Number
- 127502-06-1
- Unique Ingredient Identifier
- 3J0KPB596Q
Overview
Tetrofosmin was developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds. It presents a molecular formula of 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane. Tetrofosmin is part of the group of diphosphines. Tetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.
Background
Tetrofosmin was developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds. It presents a molecular formula of 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane. Tetrofosmin is part of the group of diphosphines. Tetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.
Indication
Tetrofosmin is indicated to be used as a complex with technetium Tc-99m for scintigraphic imaging of the myocardium following separate administrations under exercise and/or resting conditions. It helps in the delineation of regions of reversible myocardial ischemia in absence of infarcted myocardium. This complex is also used for scintigraphic imaging of the myocardium to identify changes in perfusion induced by pharmacologic stress in patients with known or suspected coronary artery disease. This complex is indicated for the assessment of left ventricular function in patients evaluated for heart disease.
Associated Conditions
- Breast Cancer
- Hypoperfusion
- Myocardial Infarction
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|
No clinical trials found
No clinical trials found for this drug
FDA Approved Products
Product Name | Manufacturer | Route | Strength | Approved | NDC Code |
|---|---|---|---|---|---|
INTRAVENOUS | 0.23 mg in 1 1 | 2022/12/12 | 17156-024 | ||
INTRAVENOUS | 0.35 mg in 1 1 | 2012/07/03 | 51808-223 | ||
INTRAVENOUS | 1.38 mg in 1 1 | 2022/12/12 | 17156-026 | ||
INTRAVENOUS | 0.35 mg in 1 1 | 2012/07/02 | 51808-223 |
EMA Approved Products
Medicine Name | EMA Number | Auth. Holder | Country | Drug Type | Status | Issued | Opinion | Revision |
|---|
No EMA products found
No EMA products found for this drug
HSA Approved Products
Product Name | Manufacturer | Dosage Form | Strength | Approved | Approval No. |
|---|---|---|---|---|---|
INJECTION, POWDER, FOR SOLUTION | 0.23 mg/vial | 2002/02/25 | SIN11820P |
NMPA Approved Products
Product Name | Approval No. | Manufacturer | Dosage Form | Trade Name | Strength | Type | Status | Date | Import |
|---|---|---|---|---|---|---|---|---|---|
国药准字H20080758 | N/A | N/A | 370--1110MBq | Chemical Drug | Approved | 2008/11/04 | Domestic | ||
国药准字H20244314 | 注射剂 | N/A | 不高于1500MBq/ml | Chemical Drug | Approved | 2024/06/28 | Domestic |
PPB Approved Products
Product Name | Registration Code | Company | Category | Sale Type | Reg. Date |
|---|
No PPB products found
No PPB products found for this drug
TGA Approved Products
Product Name | ARTG ID | Sponsor | Status | Reg. Date | Ingredient |
|---|---|---|---|---|---|
60998 | Active | 1997/08/26 | tetrofosmin |