Teniposide
- Generic Name
- Teniposide
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C32H32O13S
- CAS Number
- 29767-20-2
- Unique Ingredient Identifier
- 957E6438QA
- Background
Teniposide is a semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent cells from entering into the mitotic phase of ...
- Indication
Teniposide is used for the treatment of refractory acute lymphoblastic leukaemia
- Associated Conditions
- Refractory Lymphoblastic Leukemia, Acute, Childhood
- Associated Therapies
- -
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