Praziquantel

Generic Name
Praziquantel
Brand Names
Biltricide
Drug Type
Small Molecule
Chemical Formula
C19H24N2O2
CAS Number
55268-74-1
Unique Ingredient Identifier
6490C9U457
Background

An anthelmintic used in most schistosome and many cestode infestations.

Indication

For the treatment of infections due to all species of schistosoma.

Associated Conditions
Cestode infections, Cysticercosis, Liver fluke infection, Trematode infections, Schistosoma infection
Associated Therapies
-

Schistosoma Haematobium Infections and Praziquantel

Phase 3
Completed
Conditions
Interventions
First Posted Date
2012-03-20
Last Posted Date
2013-01-17
Lead Sponsor
University of Khartoum
Target Recruit Count
520
Registration Number
NCT01558336
Locations
🇸🇩

Al Salamania, Al Salamania, Nile, Sudan

Praziquantel-Pharmacokinetic Study

Phase 1
Completed
Conditions
Interventions
First Posted Date
2011-02-03
Last Posted Date
2019-01-18
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
47
Registration Number
NCT01288872
Locations
🇵🇭

Research Institute for Tropical Medicine - Health Compound, Muntinlupa City, National Capital Region, Philippines

Prevention of Female Genital Schistosomiasis (FGS) in Rural High-endemic South Africa

First Posted Date
2010-07-01
Last Posted Date
2017-09-19
Lead Sponsor
Oslo University Hospital
Target Recruit Count
6500
Registration Number
NCT01154907
Locations
🇿🇦

University of KwaZulu Natal, Durban, KwaZulu Natal, South Africa

A Randomised Trial of Artesunate-sulfamethoxypyrazine/Pyrimethamine Versus Praziquantel for the Treatment of S. Mansoni

First Posted Date
2010-01-22
Last Posted Date
2010-01-22
Lead Sponsor
Kenya Medical Research Institute
Target Recruit Count
212
Registration Number
NCT01054651
Locations
🇰🇪

KEMRI Centre for Global Health Research, Kisumu, Kenya

Comparing Praziquantel Versus Artesunate + Sulfamethoxypyrazine/Pyrimethamine for Treating Schistosomiasis

Phase 2
Completed
Conditions
First Posted Date
2007-08-01
Last Posted Date
2008-01-18
Lead Sponsor
Dafra Pharma
Target Recruit Count
800
Registration Number
NCT00510159

Empiric Therapy of Helminth Co-infection to Reduce HIV-1 Disease Progression

First Posted Date
2007-07-26
Last Posted Date
2014-11-20
Lead Sponsor
University of Washington
Target Recruit Count
948
Registration Number
NCT00507221
Locations
🇰🇪

Kenya Medical Research Institute, Nairobi, Kenya

S. Japonicum and Pregnancy Outcomes

Phase 2
Completed
Conditions
Interventions
First Posted Date
2007-06-15
Last Posted Date
2016-01-26
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
370
Registration Number
NCT00486863
Locations
🇵🇭

Research Institute for Tropical Medicine - Health Compound, Muntinlupa City, National Capital Region, Philippines

Neurocysticercosis: Combined Treatment With Praziquantel (PZQ) and Albendazole (ABZ)

First Posted Date
2007-02-28
Last Posted Date
2015-06-11
Lead Sponsor
Universidad Peruana Cayetano Heredia
Target Recruit Count
156
Registration Number
NCT00441285
Locations
🇵🇪

Universidad Peruana Cayetano Heredia, Lima, Peru

🇵🇪

Hospital Nacional Edgardo Rebagliati, Lima, Peru

🇵🇪

Hospital Nacional Cayetano Heredia, Lima, Peru

and more 2 locations

Influence of Transmission Season on Outcome of Treatment of Schistosoma Haematobium Infection in Mozambique

Not Applicable
Completed
Conditions
First Posted Date
2005-10-04
Last Posted Date
2007-04-20
Lead Sponsor
DBL -Institute for Health Research and Development
Target Recruit Count
520
Registration Number
NCT00231322
Locations
🇲🇿

Matola, Maputo, Maputo Province, Mozambique

The Effect of Praziquantel Treatment on Schistosoma Mansoni Morbidity and re-Infection Along Lake Victoria, Uganda

Not Applicable
Completed
Conditions
First Posted Date
2005-09-22
Last Posted Date
2008-02-21
Lead Sponsor
DBL -Institute for Health Research and Development
Target Recruit Count
540
Registration Number
NCT00215267
Locations
🇺🇬

Musoli village, Busuyi parish, Mayuge District, Uganda

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