Chlorthalidone
- Generic Name
- Chlorthalidone
- Brand Names
- Edarbyclor, Tenoretic, Thalitone
- Drug Type
- Small Molecule
- Chemical Formula
- C14H11ClN2O4S
- CAS Number
- 77-36-1
- Unique Ingredient Identifier
- Q0MQD1073Q
- Background
Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through inhibition of the Na+/Cl− symporter in the distal convoluted tubule cells in t...
- Indication
Chlorthalidone is indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension.
Chlorthalidone is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy....
- Associated Conditions
- Calcium Nephrolithiasis, Edema, Hypertension
- Associated Therapies
- -
Study links polygenic scores to hypertension treatment outcomes
Utility of a Systolic Blood Pressure Polygenic Risk Score With Chlorthalidone Response
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