Overview
Estrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone. It is produced in vivo from androstenedione or from testosterone via estradiol. It is produced primarily in the ovaries, placenta, and in peripheral tissues (especially adipose tissue) through conversion of adrostenedione. Estrone may be further metabolized to 16-alpha-hydroxyestrone, which may be reduced to estriol by estradiol dehydrogenase.
Indication
For management of perimenopausal and postmenopausal symptoms.
Associated Conditions
- Vulvo Vaginal Atrophy
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|
No clinical trials found
No clinical trials found for this drug
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| Dr. Donna Restivo DC | 62185-0050 | ORAL | 8 [hp_X] in 1 mL | 5/23/2025 | |
| Deseret Biologicals, Inc. | 43742-1507 | ORAL | 8 [hp_X] in 1 mL | 5/27/2025 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| No PPB approvals found for this drug. | |||||
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| No TGA approvals found for this drug. | |||||
Health Canada Drug Approvals
Approved Product | Company | DIN | Dosage Form | Strength | Market Date |
|---|---|---|---|---|---|
| FOLLICULINUM | seroyal international inc. | 02233755 | Pellet
,
Granules
,
Tablet
,
Drops
,
Globules
,
Liquid - Oral | 3 X | 4/6/1998 |
| ESTRAGYN VAGINAL CREAM | searchlight pharma inc | 00727369 | Cream - Vaginal | 0.1 % / W/W | 12/31/1987 |
| OESTRILIN CREME VAGINALE 1MG | desbergers ltée, division of technilab inc. | 00006149 | Cream - Vaginal | 1 MG / G | 12/31/1968 |
| OESTRILIN CONES VAGINAUX | desbergers ltée, division of technilab inc. | 00006211 | Suppository - Vaginal | .25 MG / SUP | 12/31/1951 |
| CIMICIFUGA PLEX | seroyal international inc. | 02235035 | Liquid
,
Drops
,
Granules
,
Syrup
,
Pellet
,
Tablet - Oral | 12 X | 4/6/1998 |
CIMA AEMPS Drug Approvals
Approved Product | Company | Registration Number | Pharmaceutical Form | Prescription Type | Status |
|---|---|---|---|---|---|
| No CIMA AEMPS (Spain) approvals found for this drug. | |||||
Philippines FDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Philippines FDA approvals found for this drug. | |||||
Saudi SFDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Saudi SFDA approvals found for this drug. | |||||
Malaysia NPRA Drug Approvals
Approved Product | Company | Registration Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Malaysia NPRA approvals found for this drug. | |||||
UK EMC Drug Information
Medicine Name | MA Holder | MA Number | Pharmaceutical Form | Active Ingredient | Authorization Date |
|---|---|---|---|---|---|
| No UK EMC drug information found for this drug. | |||||
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