Flutamide

Generic Name
Flutamide
Brand Names
Eulexin
Drug Type
Small Molecule
Chemical Formula
C11H11F3N2O3
CAS Number
13311-84-7
Unique Ingredient Identifier
76W6J0943E
Background

An antiandrogen with about the same potency as cyproterone in rodent and canine species.

Indication

For the management of locally confined Stage B2-C and Stage D2 metastatic carcinoma of the prostate

Associated Conditions
Stage B2-C metastatic Carcinoma of the Prostate, Stage D2 metastatic Carcinoma of the Prostate
Associated Therapies
-

Finasteride and Flutamide in Pre-surgical Trial in Prostate Cancer.

First Posted Date
2024-09-19
Last Posted Date
2024-09-19
Lead Sponsor
Ente Ospedaliero Ospedali Galliera
Target Recruit Count
125
Registration Number
NCT06601205
Locations
🇮🇹

Medical Oncology Ente Ospedaliero Ospedali Galliera, Genova, Italy

Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score

First Posted Date
2021-09-20
Last Posted Date
2024-11-27
Lead Sponsor
NRG Oncology
Target Recruit Count
2050
Registration Number
NCT05050084
Locations
🇺🇸

Arizona Center for Cancer Care - Gilbert, Gilbert, Arizona, United States

🇺🇸

Arizona Center for Cancer Care-Peoria, Peoria, Arizona, United States

🇺🇸

Arizona Center for Cancer Care - Phoenix, Phoenix, Arizona, United States

and more 532 locations

Androgen Blockade and Progesterone Augmentation of Gonadotropin Secretion

First Posted Date
2020-10-22
Last Posted Date
2023-11-02
Lead Sponsor
University of Virginia
Target Recruit Count
10
Registration Number
NCT04597099
Locations
🇺🇸

University of Virginia, Charlottesville, Virginia, United States

Androgen Deprivation Therapy on Bone Mineral Density Change in Prostate Cancer Patients

First Posted Date
2020-01-30
Last Posted Date
2021-07-29
Lead Sponsor
Wonju Severance Christian Hospital
Target Recruit Count
164
Registration Number
NCT04248621
Locations
🇰🇷

Department of Urology, Chonnam National University, School of Medicine, Gwangju, Korea, Republic of

🇰🇷

Department of Urology, Kyungpook National University, School of Medicine, Daegu, Korea, Republic of

🇰🇷

Department of Urology, Eulji University, College of Medicine, Daejeon, Korea, Republic of

and more 7 locations

Assessing Induction of Double Strand Breaks With Androgen Receptor Partial Agonist in Patients on Androgen Suppression

Early Phase 1
Active, not recruiting
Conditions
Interventions
First Posted Date
2018-04-25
Last Posted Date
2024-11-22
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Target Recruit Count
24
Registration Number
NCT03507608
Locations
🇺🇸

SKCCC at Johns Hopkins, Baltimore, Maryland, United States

Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by Surgery

First Posted Date
2017-03-06
Last Posted Date
2024-11-29
Lead Sponsor
NRG Oncology
Target Recruit Count
612
Registration Number
NCT03070886
Locations
🇺🇸

Kaiser Permanente Sacramento Medical Center, Sacramento, California, United States

🇺🇸

Henry Ford Health Saint John Hospital, Detroit, Michigan, United States

🇺🇸

MyMichigan Medical Center Saginaw, Saginaw, Michigan, United States

and more 311 locations

Study on Enzalutamide and Flutamide in Patients With Castration Resistant Prostate Cancer

First Posted Date
2016-09-29
Last Posted Date
2024-12-09
Lead Sponsor
Astellas Pharma Inc
Target Recruit Count
206
Registration Number
NCT02918968
Locations
🇯🇵

Site JP00051, Iizuka, Fukuoka, Japan

🇯🇵

Site JP00019, Sagamihara, Kanagawa, Japan

🇯🇵

Site JP00024, Nagoya, Aichi, Japan

and more 44 locations

Androgen Deprivation Therapy or Androgen Deprivation Therapy Plus Definitive Treatment (Radiation or Surgery)

First Posted Date
2016-04-19
Last Posted Date
2020-07-07
Lead Sponsor
Fudan University
Target Recruit Count
200
Registration Number
NCT02742675
Locations
🇨🇳

Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China

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