Aminophylline
- Generic Name
- Aminophylline
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C16H24N10O4
- CAS Number
- 317-34-0
- Unique Ingredient Identifier
- 27Y3KJK423
- Background
Aminophylline is a drug combination that contains theophylline and ethylenediamine in a 2:1 ratio. Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Similar to other theophyllines, aminophylline is indicated for the treatment of lung diseases such as asthma, ch...
- Indication
For the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.
- Associated Conditions
- Acute Exacerbation of Chronic Bronchitis (AECB), Asthma, Bronchial Asthma, Bronchospasm, Chronic Bronchitis, Exacerbation of asthma
- Associated Therapies
- -
Prevention of Cisplatin-induced Nephrotoxicity
- Conditions
- Interventions
- First Posted Date
- 2024-01-09
- Last Posted Date
- 2024-01-09
- Lead Sponsor
- Mahidol University
- Target Recruit Count
- 24
- Registration Number
- NCT06196853
- Locations
- 🇹🇭
Siriraj hospital, Mahidol university, Bangkok, Thailand
Effects of Aminophylline Bolus on TCI (Target Controlled Infusion) Concentrations at Burst Suppression Occurence
- First Posted Date
- 2023-11-18
- Last Posted Date
- 2024-04-25
- Lead Sponsor
- University of Padova
- Target Recruit Count
- 32
- Registration Number
- NCT06134037
- Locations
- 🇮🇹
Treviso Regional Hospital, Treviso, TV, Italy
Effects of Aminophylline Bolus on TCI (Target Controlled Infusion) Concentrations at Return of Responsiveness
- First Posted Date
- 2023-10-24
- Last Posted Date
- 2024-04-25
- Lead Sponsor
- University of Padova
- Target Recruit Count
- 48
- Registration Number
- NCT06098196
- Locations
- 🇮🇹
ULSS2 Marca Trevigiana, Treviso, Italy
🇮🇹ULSS 2 Marca Trevigiana, Treviso, Tv, Italy
Diuretic Efficacy of Aminophylline and Furosemide Combination vs Furosemide Alone in Critically Ill Adults
- First Posted Date
- 2023-07-06
- Last Posted Date
- 2023-07-11
- Lead Sponsor
- University of Malaya
- Target Recruit Count
- 132
- Registration Number
- NCT05933642
- Locations
- 🇲🇾
University of Malaya, Kuala Lumpur, Malaysia
Postdural Puncture Headache Relief With Aminophylline and SPGB
- Conditions
- Interventions
- First Posted Date
- 2022-09-23
- Last Posted Date
- 2023-01-11
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 75
- Registration Number
- NCT05552404
- Locations
- 🇪🇬
faculty of medicine, Ain Shams University, Cairo, Egypt
The Effect of Preoperative Aminophylline
- First Posted Date
- 2019-11-05
- Last Posted Date
- 2019-11-05
- Lead Sponsor
- Beni-Suef University
- Target Recruit Count
- 45
- Registration Number
- NCT04151381
- Locations
- 🇪🇬
Beni-Suef University Hospital, Banī Suwayf, Egypt
🇪🇬Faculty of Medicine, Beni-SuefUniversity, Banī Suwayf, Egypt
Preventing Acute Kidney Injury (AKI) in Pediatric Patients
- First Posted Date
- 2019-04-01
- Last Posted Date
- 2022-04-18
- Lead Sponsor
- Le Bonheur Children's Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT03897335
- Locations
- 🇺🇸
LeBonheur Children's Hospital, Memphis, Tennessee, United States
Non-invasive Ventilation vs. Standard Therapy for Children Hospitalized With an Acute Exacerbation of Asthma
- First Posted Date
- 2017-09-28
- Last Posted Date
- 2018-05-02
- Lead Sponsor
- University of British Columbia
- Target Recruit Count
- 100
- Registration Number
- NCT03296579
Progesterone and Aminophylline for the Prevention of Preterm Labour
- First Posted Date
- 2017-05-15
- Last Posted Date
- 2018-02-28
- Lead Sponsor
- St Stephens Aids Trust
- Target Recruit Count
- 70
- Registration Number
- NCT03152942
- Locations
- 🇬🇧
Chelsea and Westminster Hospital, London, United Kingdom
Effects of Aminophylline on Renal Function and Urine Volume of AKI Patient
- Conditions
- Interventions
- First Posted Date
- 2016-12-06
- Last Posted Date
- 2016-12-06
- Target Recruit Count
- 60
- Registration Number
- NCT02983422
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.