MedPath

Polatuzumab

Generic Name
Polatuzumab

A Study of Glofitamab-based Treatment in People With Diffuse Large B-cell Lymphoma

Phase 2
Recruiting
Conditions
Diffuse Large B Cell Lymphoma (DLBCL)
High Grade B Cell Lymphoma
Interventions
First Posted Date
2025-03-25
Last Posted Date
2025-03-28
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Target Recruit Count
42
Registration Number
NCT06765317
Locations
🇺🇸

Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge, New Jersey, United States

🇺🇸

Memorial Sloan Kettering Monmouth (Limited Protocol Activities), Middletown, New Jersey, United States

🇺🇸

Memorial Sloan Kettering Bergen (Limited Protocol Activities), Montvale, New Jersey, United States

and more 4 locations

A Phase II Study of Glofitamab Plus Polatuzumab-R-CHP for Patients with High-risk Diffuse Large B-cell Lymphoma

Phase 2
Active, not recruiting
Conditions
Lymphoma
Lymphoma, Large B-Cell, Diffuse
Interventions
First Posted Date
2023-04-05
Last Posted Date
2025-03-14
Lead Sponsor
Jennifer Crombie, MD
Target Recruit Count
41
Registration Number
NCT05800366
Locations
🇺🇸

University of Miami Sylvester Cancer Center, Miami, Florida, United States

🇺🇸

Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

CAR-T Cell Therapy, Mosunetuzumab and Polatuzumab for Treatment of Refractory/Relapsed Aggressive Non-Hodgkin's Lymphoma (NHL).

Phase 2
Recruiting
Conditions
Refractory Non-Hodgkin Lymphoma
Relapsed Non Hodgkin Lymphoma
Aggressive Non-Hodgkin Lymphoma
Interventions
Biological: CAR-T Cell Therapy
First Posted Date
2022-03-02
Last Posted Date
2025-03-25
Lead Sponsor
Lazaros Lekakis
Target Recruit Count
22
Registration Number
NCT05260957
Locations
🇺🇸

University of Miami, Miami, Florida, United States

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid in Combination With Polatuzumab (ViPOR-P) in Relapsed/Refractory B-cell Lymphoma

Phase 1
Recruiting
Conditions
Lymphoma
Non-Hodgkin Lymphoma
Diffuse Large B-Cell Lymphoma
Burkitt Lymphoma
Interventions
First Posted Date
2021-02-05
Last Posted Date
2025-03-13
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
55
Registration Number
NCT04739813
Locations
🇺🇸

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

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