Gonadorelin
- Generic Name
- Gonadorelin
- Brand Names
- Lutrepulse
- Drug Type
- Small Molecule
- Chemical Formula
- C55H75N17O13
- CAS Number
- 33515-09-2
- Unique Ingredient Identifier
- 9O7312W37G
- Background
Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pituitary.
- Indication
For evaluating the functional capacity and response of the gonadotropes of the anterior pituitary also for evaluating residual gonadotropic function of the pituitary following removal of a pituitary tumor by surgery and/or irradiation.
- Associated Conditions
- -
- Associated Therapies
- Ovulation induction therapy
Kisspeptin Administration in the Adult
- Conditions
- Kallmann SyndromeGnRH DeficiencyPolycystic Ovarian SyndromeHyperprolactinemiaHypogonadotropic HypogonadismPCOS
- Interventions
- Drug: kisspeptin 112-121Drug: GnRH
- First Posted Date
- 2009-06-05
- Last Posted Date
- 2024-07-31
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 256
- Registration Number
- NCT00914823
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Rapid Hormonal Cycling as Treatment for Patients With Prostate Cancer: The Men's Cycle
- Conditions
- Hormonal CyclingProstateCancer
- Interventions
- Drug: GnRHDrug: KetoconazoleDrug: BicalutamideDrug: Testosterone transdermal gelDrug: Estrogen transdermal patch
- First Posted Date
- 2008-01-07
- Last Posted Date
- 2016-03-25
- Lead Sponsor
- Memorial Sloan Kettering Cancer Center
- Target Recruit Count
- 36
- Registration Number
- NCT00586898
- Locations
- 🇺🇸
Memorial Sloan Kettering Cancer Center, New York, New York, United States
The Effects of Aging and Estrogen on the Pituitary
- First Posted Date
- 2006-10-11
- Last Posted Date
- 2017-04-13
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 19
- Registration Number
- NCT00386022
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Pulsatile GnRH in Anovulatory Infertility
- Conditions
- Kallmann's SyndromeHypogonadotropic HypogonadismAmenorrhea
- Interventions
- Drug: GnRHDevice: Pump
- First Posted Date
- 2006-10-03
- Last Posted Date
- 2017-07-12
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 270
- Registration Number
- NCT00383656
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Drug Development Updates
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