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Arbaclofen

Generic Name
Arbaclofen
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C10H12ClNO2
CAS Number
69308-37-8
Unique Ingredient Identifier
NYU6UTW25B
Background

Arbaclofen, or STX209, is the R-enantiomer of baclofen. It is believed to be a selective gamma-amino butyric acid type B receptor agonist, and has been investigated as a treatment for autism spectrum disorder and fragile X syndrome in randomized, double blind, placebo controlled trials. It has also been investigated as a treatment for spasticity due to multiple sclerosis and spinal cord injury. Arbaclofen was investigated as a treatment for gastroesophageal reflux disease (GERD); however, with disappointing results.

Indication

Investigated in clinical trials as a potential treatment for spasticity in multiple sclerosis, autism spectrum disorder, and social withdrawal in fragile X syndrome.

Associated Conditions
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Associated Therapies
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