Fentanyl

Generic Name
Fentanyl
Brand Names
Abstral, Actiq, Duragesic, Effentora, Fentora, Instanyl, Lazanda, Sublimaze, Subsys, PecFent
Drug Type
Small Molecule
Chemical Formula
C22H28N2O
CAS Number
437-38-7
Unique Ingredient Identifier
UF599785JZ
Background

Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia. Fentanyl is related to other opioids like morphine and oxycodone.
...

Indication

Fentanyl intravenous or intramuscular injections are indicated for short term analgesia during induction, maintenance, and recovery from general or regional anesthesia. These injections are also used with a neuroleptic for premedication, induction, and as an adjunct to maintenance of anesthesia. Finally, fentanyl intravenous or intramuscular injections are u...

Associated Conditions
Cancer Related Pain (Breakthrough Pain), Severe, Chronic Pain
Associated Therapies
Anesthetic premedication therapy, Anesthetics Agent, General Anesthesia, Induction of anesthesia therapy, Maintenance of anesthesia therapy, Regional Anesthesia therapy
Clinical Trials
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Efficacy and Safety of Remifentanil for Mechanically Ventilated Patients in Intensive Care Unit

Phase 3
Recruiting
Conditions
Analgesia
Interventions
Drug: Remifentanil
Drug: Fentanyl
First Posted Date
2022-12-08
Last Posted Date
2022-12-08
Lead Sponsor
Southeast University, China
Target Recruit Count
138
Registration Number
NCT05641909
Locations
🇨🇳

Anhui Provincial People's Hospital, Hefei, Anhui, China

🇨🇳

The First Affiliated Hospital of Chongqing Medical University, Chongqing, Chongqing, China

🇨🇳

First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China

and more 15 locations

Muscle Reflex Inhibition in Hypoxic Exercise

Not Applicable
Not yet recruiting
Conditions
Dyspnea
Muscle Strain
Interventions
Other: Saline
Drug: Fentanyl
First Posted Date
2022-11-17
Last Posted Date
2022-11-23
Lead Sponsor
University of British Columbia
Target Recruit Count
14
Registration Number
NCT05619887
Locations
🇨🇦

University of British Columbia - Okanagan Campus, Kelowna, British Columbia, Canada

The NONA-LISA Trial

First Posted Date
2022-11-08
Last Posted Date
2024-07-16
Lead Sponsor
Rigshospitalet, Denmark
Target Recruit Count
324
Registration Number
NCT05609877
Locations
🇩🇰

Neonatalafsnittet, Børn- og Ungeafdelingen, Reberbansgade 15, Aalborg, Denmark

🇩🇰

Department of Paediatrics (Intensive Care Neonatology) and Perinatal Research Unit, Aarhus, Denmark

🇩🇰

Department of Neonatal and Pediatric Intensive Care, Blegdamsvej 9, Copenhagen, Denmark

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Ultrasound Guided Erector Spinae Block vs Thoracolumbar Interfascial Plane Block

First Posted Date
2022-10-27
Last Posted Date
2024-11-25
Lead Sponsor
Tanta University
Target Recruit Count
180
Registration Number
NCT05596227
Locations
🇪🇬

Mona Mohamed Mogahed, Tanta, Elgharbia, Egypt

Ultrasound Guided Psoas Compartment Block vs Suprainguinal Fascia Iliaca Compartment Block

First Posted Date
2022-09-16
Last Posted Date
2022-09-30
Lead Sponsor
Tanta University
Target Recruit Count
85
Registration Number
NCT05543109
Locations
🇪🇬

Mona Mohamed Mogahed, Tanta, Elgharbia, Egypt

Fentanyl as an Adjuvant to Peribulbar Block in Buckle or Squint Surgeries

Early Phase 1
Recruiting
Conditions
Pain
Interventions
Drug: Fentanyl
First Posted Date
2022-09-14
Last Posted Date
2022-10-25
Lead Sponsor
Research Institute of Ophthalmology, Egypt
Target Recruit Count
50
Registration Number
NCT05539911
Locations
🇪🇬

Research Institute of Ophthalmology, Giza, Egypt

Fentanyl Versus Morphine in Spinal Anesthesia for Caesarian Section - Study on Analgesia, Side Effects and Patient 's Satisfaction

Completed
Conditions
Anesthesia
Interventions
Drug: Fentanyl
Drug: Morphine
First Posted Date
2022-09-08
Last Posted Date
2023-08-30
Lead Sponsor
Dr. Mihai Octavian Botea
Target Recruit Count
160
Registration Number
NCT05533229
Locations
🇷🇴

University of Oradea, Pelican Clinic Hospital, Oradea, Bihor, Romania

Effect of Remimazolam vs Sevoflurane Anesthesia on Incidence of Emergence Agitation and Complications in Children Undergoing Ophthalmic Surgery

First Posted Date
2022-09-02
Last Posted Date
2023-03-24
Lead Sponsor
Second Affiliated Hospital of Nanchang University
Target Recruit Count
110
Registration Number
NCT05527314
Locations
🇨🇳

the Second Affiliated Hospital of Nanchang University, Nanchang University, Nanchang, Jiangxi, China

A Comparison Between Ketamine-lidocaine Versus Ketamine-fentanyl for Induction on the Hemodynamic Effects in Patients With Coronary Artery Disease

Not Applicable
Recruiting
Conditions
Induction of General Anesthesia
Interventions
Drug: Lidocaine IV
Drug: Fentanyl
First Posted Date
2022-08-16
Last Posted Date
2022-10-20
Lead Sponsor
Kasr El Aini Hospital
Target Recruit Count
100
Registration Number
NCT05502211
Locations
🇪🇬

Kasr al ainy, Cairo, Egypt

🇪🇬

Kasr Al Ainy, Cairo, Egypt

Effectiveness of Clonidine, Dexmedetomidine, and Fentanyl Adjuncts for Labor Epidural Analgesia

First Posted Date
2022-08-04
Last Posted Date
2023-10-10
Lead Sponsor
Grace Lim, MD, MS
Target Recruit Count
88
Registration Number
NCT05487196
Locations
🇺🇸

UPMC Magee-Womens Hospital, Pittsburgh, Pennsylvania, United States

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