A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (Dorland, 28th ed)
The primary popular claim made for inosine, that it enhances exercise and athletic performance, is refuted by the available research data. There is some preliminary evidence that inosine may have some neurorestorative, anti-inflammatory, immunomodulatory and cardioprotective effects.
Emory University affiliated newborn intensive care units, Atlanta, Georgia, United States
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
Univeristy of Southern California/Good Samaritan Hospital, Los Angeles, California, United States
University of Iowa Hospital & Clinics, Iowa City, Iowa, United States
University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States
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