Inosine

Generic Name
Inosine
Brand Names
Rejuvesol
Drug Type
Small Molecule
Chemical Formula
C10H12N4O5
CAS Number
58-63-9
Unique Ingredient Identifier
5A614L51CT
Background

A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (Dorland, 28th ed)

Indication

The primary popular claim made for inosine, that it enhances exercise and athletic performance, is refuted by the available research data. There is some preliminary evidence that inosine may have some neurorestorative, anti-inflammatory, immunomodulatory and cardioprotective effects.

Associated Conditions
-
Associated Therapies
Rejuvenation of a unit of RBC

NO Need to Ventilate: A Trial of Non-invasive Inhaled Nitric Oxide in Persistent Pulmonary Hypertension of the Newborn

Not Applicable
Completed
Conditions
First Posted Date
2005-08-31
Last Posted Date
2014-05-29
Lead Sponsor
Emory University
Target Recruit Count
400
Registration Number
NCT00139217
Locations
🇺🇸

Emory University affiliated newborn intensive care units, Atlanta, Georgia, United States

Treatment of Multiple Sclerosis Using Over the Counter Inosine

Phase 2
Completed
Conditions
First Posted Date
2003-08-19
Last Posted Date
2006-03-17
Lead Sponsor
National Center for Complementary and Integrative Health (NCCIH)
Target Recruit Count
30
Registration Number
NCT00067327
Locations
🇺🇸

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

Inhaled Nitric Oxide for Preventing Chronic Lung Disease in Premature Infants

First Posted Date
2000-10-13
Last Posted Date
2015-10-06
Lead Sponsor
University of Colorado, Denver
Target Recruit Count
793
Registration Number
NCT00006401
Locations
🇺🇸

Univeristy of Southern California/Good Samaritan Hospital, Los Angeles, California, United States

🇺🇸

University of Iowa Hospital & Clinics, Iowa City, Iowa, United States

🇺🇸

University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States

and more 11 locations
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