MedPath

Navitoclax

Generic Name
Navitoclax
Drug Type
Small Molecule
Chemical Formula
C47H55ClF3N5O6S3
CAS Number
923564-51-6
Unique Ingredient Identifier
XKJ5VVK2WD

Overview

Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among others. Navitoclax is an orally bioavailable small molecule inhibitor of Bcl-2 family proteins. It is a substance being studied in the treatment of lymphomas and other types of cancer. It blocks some of the enzymes that keep cancer cells from dying.

Indication

No indication information available.

Associated Conditions

No associated conditions information available.

Clinical Trials

Title
Posted
Study ID
Phase
Status
Sponsor
2023/08/23
Phase 1
Withdrawn
2023/05/18
Phase 2
Active, not recruiting
Peter MacCallum Cancer Centre, Australia
2023/02/23
Phase 1
Withdrawn
Princess Maxima Center for Pediatric Oncology
2022/10/03
Phase 1
Active, not recruiting
2022/07/13
Phase 1
Active, not recruiting
Jacqueline Garcia, MD
2022/05/03
Phase 1
Active, not recruiting
2022/02/03
Phase 1
Active, not recruiting
City of Hope Medical Center
2022/01/31
N/A
NO_LONGER_AVAILABLE
Kathleen Ludwig
2022/01/14
Phase 1
Active, not recruiting
2021/09/23
Phase 1
Not yet recruiting

FDA Drug Approvals

Approved Product
Manufacturer
NDC Code
Route
Strength
Effective Date
No FDA approvals found for this drug.

EMA Drug Approvals

Approved Product
Authorization Holder
Status
Issued Date
No EMA approvals found for this drug.

HSA Drug Approvals

Approved Product
Manufacturer
Approval Number
Dosage Form
Strength
Approval Date
No HSA approvals found for this drug.

NMPA Drug Approvals

Approved Product
Company
Approval Number
Drug Type
Dosage Form
Approval Date
No NMPA approvals found for this drug.

PPB Drug Approvals

Approved Product
Registration No.
Company
Licence No.
Strength
Registration Date
No PPB approvals found for this drug.

TGA Drug Approvals

Approved Product
ARTG ID
Sponsor
Registration Type
Status
Registration Date
No TGA approvals found for this drug.

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