Overview
Dovitinib is an orally active small molecule that exhibits potent inhibitory activity against multiple RTKs involved in tumor growth and angiogenesis. Preclinical data show that dovitinib works to inhibit multiple kinases associated with different cancers, including acute myeloid leukemia (AML) and multiple myeloma. Chiron currently has three ongoing Phase I clinical trials for dovitinib.
Indication
Investigated for use/treatment in multiple myeloma and solid tumors.
Associated Conditions
No associated conditions information available.
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2016/03/28 | Phase 1 | Terminated | National Cancer Centre, Singapore | ||
2014/10/20 | Phase 1 | Withdrawn | |||
2014/04/17 | Phase 2 | Completed | |||
2014/04/09 | Phase 2 | Withdrawn | Academic and Community Cancer Research United | ||
2014/02/19 | Phase 2 | Withdrawn | Oscar Goodman, Jr. | ||
2014/01/29 | Phase 1 | Withdrawn | |||
2013/11/26 | Phase 2 | Terminated | |||
2013/10/30 | Phase 1 | UNKNOWN | PD Dr. Martin Glas | ||
2013/10/17 | Phase 2 | Completed | |||
2013/08/13 | Phase 1 | Completed |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| No FDA approvals found for this drug. | |||||
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| No PPB approvals found for this drug. | |||||
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| No TGA approvals found for this drug. | |||||
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