Colistimethate
- Generic Name
- Colistimethate
- Brand Names
- Colobreathe, Coly Mycin M, Xylistin
- Drug Type
- Small Molecule
- Chemical Formula
- C58H105N16O28S5
- CAS Number
- 12705-41-8
- Unique Ingredient Identifier
- DL2R53P963
- Background
Colistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms. Colistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aeruginosa.
- Indication
For the treatment of acute or chronic infections due to sensitive strains of certain gram-negative bacilli, particularly Pseudomonas aeruginosa.
- Associated Conditions
- Bacterial Infections
- Associated Therapies
- -
Evaluation of Pharmacokinetic and Pharmacodynamic Properties of Intravenous Colistimethate Sodium
- First Posted Date
- 2014-11-11
- Last Posted Date
- 2019-06-24
- Lead Sponsor
- University of Colorado, Denver
- Target Recruit Count
- 16
- Registration Number
- NCT02288429
- Locations
- 🇺🇸
University of Colorado Hospital, Aurora, California, United States
Aerosolized and Intravenous Colistin in Healthy Adults
- Conditions
- Pneumococcal InfectionPneumoniaPathogen Resistance
- Interventions
- First Posted Date
- 2013-05-29
- Last Posted Date
- 2020-03-02
- Target Recruit Count
- 27
- Registration Number
- NCT01863719
- Locations
- 🇺🇸
Johns Hopkins Bayview Medical Center - Infectious Diseases, Baltimore, Maryland, United States
🇺🇸Case Western Reserve University - Case Medical Center - Infectious Disease & HIV Medicine, Cleveland, Ohio, United States
Drug Development Updates
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