Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered. It is indicated to treat several ...
Spironolactone is indicated for the treatment of the following conditions:
As spironolactone has antiandrogenic activity, its off-label uses include the treatment of hirsutism, female pattern hair loss, and adult acne vulgaris.
Hospital of the Medical School of Botucatu, Botucatu, São Paulo, Brazil
Wolfson Medical Center, Holon, Israel
Accutest Research Laboratories (I) Pvt. Ltd., Mumbai, India
Hôpital PITIE-SALPETRIERE - Institut de Cardiologie, Paris, France
Instituto Nacional Nutricion Salvador Zubiran, Mexico, Mexico
Tufts Medical Center, Boston, Massachusetts, United States
University of Los Andes, Santiago, Chile
University Erlangen-Nürnberg, Nephrology and Hypertension, Erlangen, Germany
Instituto Nacional de Cardiologia Ignacio Chavez, Mexico, DF, Mexico
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