Colistin
- Generic Name
- Colistin
- Brand Names
- Cortisporin-TC
- Drug Type
- Small Molecule
- Chemical Formula
- C52H98N16O13
- CAS Number
- 1066-17-7
- Unique Ingredient Identifier
- Z67X93HJG1
- Background
Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
- Indication
For the treatment of acute or chronic infections due to sensitive strains of certain gram-negative bacilli, particularly Pseudomonas aeruginosa.
- Associated Conditions
- Ear infection bacterial, External ear infection NOS
Comparative Study of Secondary Prophylaxis for SBP
- Conditions
- Spontaneous Bacterial PeritonitisCirrhoses, LiverAscites
- Interventions
- First Posted Date
- 2025-02-14
- Last Posted Date
- 2025-02-14
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 90
- Registration Number
- NCT06827756
- Locations
- 🇪🇬
Tanta University, Faculty of Medicine, Tanta, Egypt
Colistin Monotherapy vs Colsitin-fosfomycine in CRAB Infection
- Conditions
- Infection Due to Carbapenem Resistant Acinetobacter
- Interventions
- First Posted Date
- 2024-08-26
- Last Posted Date
- 2024-08-26
- Lead Sponsor
- Chiang Mai University
- Target Recruit Count
- 188
- Registration Number
- NCT06570850
- Locations
- 🇹🇭
Faculty of medicine, Chiang Mai university, Chiang Mai, Thailand
Colistin Dosage Prsonalization Approach
- First Posted Date
- 2024-06-25
- Last Posted Date
- 2024-06-25
- Lead Sponsor
- Mahmoud I Mostafa
- Target Recruit Count
- 100
- Registration Number
- NCT06472271
- Locations
- 🇪🇬
Cairo univrsity Hospitals, Cairo, Egypt
Cefiderocol and Ampicillin-sulbactam vs. Colistin +/- Meropenem for Carbapenem Resistant A. Baumannii
- Conditions
- Carbapenem Resistant Bacterial InfectionAcinetobacter BacteremiaAcinetobacter Pneumonia
- Interventions
- First Posted Date
- 2023-06-28
- Last Posted Date
- 2024-04-16
- Lead Sponsor
- Rambam Health Care Campus
- Target Recruit Count
- 734
- Registration Number
- NCT05922124
Aerosolized Versus Intravenous Colistin-based Antimicrobial Regimens in Hospitalized COVID-19 Patients With Bacterial Coinfection: A Randomized Controlled Trial
- Conditions
- Secondary Bacterial Infection in COVID-19 Patients
- Interventions
- First Posted Date
- 2023-01-19
- Last Posted Date
- 2023-01-19
- Lead Sponsor
- Beni-Suef University
- Target Recruit Count
- 128
- Registration Number
- NCT05689229
- Locations
- 🇪🇬
University Hospital, Banī Suwayf, Beni-Suef, Egypt
The Effect of Curcumin Against Colistin-induced Nephrotoxicity
- Conditions
- Acute Kidney InjuryDrug-Induced Nephropathy
- Interventions
- First Posted Date
- 2022-11-14
- Last Posted Date
- 2023-10-31
- Lead Sponsor
- October 6 University
- Target Recruit Count
- 214
- Registration Number
- NCT05613361
- Locations
- 🇪🇬
Cairo University Hospitals, Cairo, Egypt
Efficacy of Colistin Monotherapy Versus Colistin Plus Minocycline for Carbapenem-Resistant A. Baumannii Infection
- Conditions
- Acinetobacter Infections
- Interventions
- First Posted Date
- 2022-10-19
- Last Posted Date
- 2023-01-18
- Lead Sponsor
- Mahidol University
- Target Recruit Count
- 94
- Registration Number
- NCT05586815
- Locations
- 🇹🇭
Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
Pharmacokinetics of Colistin in Critically Ill Patients With Extracorporeal Membrane Oxygenation
- First Posted Date
- 2022-09-15
- Last Posted Date
- 2024-01-31
- Lead Sponsor
- St. Anne's University Hospital Brno, Czech Republic
- Target Recruit Count
- 8
- Registration Number
- NCT05542446
- Locations
- 🇨🇿
St. Anne's University Hospital Brno, Brno, Czech Republic, Czechia
Secondary Prophylaxis of Hepatic Encephalopathy in Cirrhotic Patients
- First Posted Date
- 2022-03-15
- Last Posted Date
- 2022-03-15
- Lead Sponsor
- Madonna Magdy Fahmy
- Target Recruit Count
- 316
- Registration Number
- NCT05279586
Ceftazidime-Avibactam Use in Critically Ill Patients With Carbapenem-Resistant Enterobacteriaceae Infections
- Conditions
- Carbapenem-Resistant Enterobacteriaceae Infection
- Interventions
- Drug: Ceftazidime-avibactam
- First Posted Date
- 2022-02-28
- Last Posted Date
- 2024-06-14
- Target Recruit Count
- 29
- Registration Number
- NCT05258851
- Locations
- 🇸🇦
King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.