Colistin

Generic Name
Colistin
Brand Names
Cortisporin-TC
Drug Type
Small Molecule
Chemical Formula
C52H98N16O13
CAS Number
1066-17-7
Unique Ingredient Identifier
Z67X93HJG1
Background

Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.

Indication

For the treatment of acute or chronic infections due to sensitive strains of certain gram-negative bacilli, particularly Pseudomonas aeruginosa.

Associated Conditions
Ear infection bacterial, External ear infection NOS
Associated Therapies
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