Colistin

Generic Name
Colistin
Brand Names
Cortisporin-TC
Drug Type
Small Molecule
Chemical Formula
C52H98N16O13
CAS Number
1066-17-7
Unique Ingredient Identifier
Z67X93HJG1
Background

Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.

Indication

For the treatment of acute or chronic infections due to sensitive strains of certain gram-negative bacilli, particularly Pseudomonas aeruginosa.

Associated Conditions
Ear infection bacterial, External ear infection NOS
Associated Therapies
-

Efficacy and Safety of Colistin for Therapy of Infections Caused by ESBL Producing K.Pneumoniae or E.Coli

Phase 3
Conditions
First Posted Date
2006-03-09
Last Posted Date
2006-05-22
Lead Sponsor
Mahidol University
Target Recruit Count
152
Registration Number
NCT00300560
Locations
🇹🇭

Division of Infectious disease and Tropical Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Bangkoknoi, Bangkok, Thailand

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