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Tapentadol

Generic Name
Tapentadol
Brand Names
Nucynta
Drug Type
Small Molecule
Chemical Formula
C14H23NO
CAS Number
175591-23-8
Unique Ingredient Identifier
H8A007M585

Overview

Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake. Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011. Used in the management of pain, tapentadol is typically reserved for patients who have limited alternative treatment options.

Background

Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake. Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011. Used in the management of pain, tapentadol is typically reserved for patients who have limited alternative treatment options.

Indication

用于治疗严重到需要阿片类镇痛剂且替代治疗不充分的急性疼痛。

Associated Conditions

  • Diabetic Peripheral Neuropathic Pain (DPN)
  • Severe Acute Pain
  • Severe Pain

FDA Approved Products

Nucynta ER
Manufacturer:Collegium Pharmaceutical, Inc.
Route:ORAL
Strength:150 mg in 1 1
Approved: 2023/12/20
NDC:24510-174
Nucynta
Manufacturer:Collegium Pharmaceutical, Inc.
Route:ORAL
Strength:50 mg in 1 1
Approved: 2023/12/21
NDC:24510-050
Nucynta ER
Manufacturer:Depo NF Sub, LLC
Route:ORAL
Strength:150 mg in 1 1
Approved: 2018/09/24
NDC:69865-250
Nucynta ER
Manufacturer:Depo NF Sub, LLC
Route:ORAL
Strength:100 mg in 1 1
Approved: 2018/09/24
NDC:69865-245
Nucynta
Manufacturer:Collegium Pharmaceutical, Inc.
Route:ORAL
Strength:100 mg in 1 1
Approved: 2023/12/21
NDC:24510-100

Singapore Approved Products

No Singapore products found for this drug

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