Ergometrine

Generic Name: Ergometrine

Drug Type: Small Molecule

Chemical Formula: C_₁₉H_₂₃N_₃O_₂

CAS Number: 60-79-7

Unique Ingredient Identifier: WH41D8433D

Overview

An ergot alkaloid with uterine and vascular smooth muscle contractile properties.

Indication

Used to treat postpartum haemorrhage and postabortion haemorrhage in patients with uterine atony.

Associated Conditions

Hemorrhage
Vasospastic Angina

Clinical Trials

Title	Posted	Study ID	Phase	Status	Sponsor
Comparing the Dose-response Profiles of Uterotonics After Initial Carbetocin Administration - an Ex-vivo Study in Desensitized Human Myometrium	2024/02/29	NCT06285409	Not Applicable	Recruiting	Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Carbetocin Versus Ergometrin in the Prevention of Postpartum Hemorrhage	2020/03/09	NCT04300452	Phase 4	UNKNOWN	National and Kapodistrian University of Athens
Carbetocin Versus Oxytocin and Ergometrine for the Prevention of Postpartum Hemorrhage	2018/07/06	NCT03578263	Not Applicable	Completed	Aswan University Hospital
Carbetocin Versus Ergometrine in the Management of Atonic Post Partum Haemorrhage (PPH) in Women Delivered Vaginally	2015/04/08	NCT02410759	Phase 3	UNKNOWN	Cairo University
Ergometrine Versus Oxytocin in the Management of Atonic Post-partum Haemorrhage (PPH) in Women Delivered Vaginally	2014/12/03	NCT02306733	Phase 3	UNKNOWN	Cairo University
In Vitro Myometrial Contractions in Laboring and Non-laboring Women	2012/09/21	NCT01689311	Not Applicable	Completed	Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Impact of Uterotonic Agents on Isolated Human Myometrium	2009/10/02	NCT00989027	Not Applicable	Completed	Samuel Lunenfeld Research Institute, Mount Sinai Hospital

FDA Drug Approvals

Approved Product	Manufacturer	NDC Code	Route	Strength	Effective Date
No FDA approvals found for this drug.

EMA Drug Approvals

Approved Product	Authorization Holder	Status	Issued Date
No EMA approvals found for this drug.

HSA Drug Approvals

Approved Product	Manufacturer	Approval Number	Dosage Form	Strength	Approval Date
SYNTOMETRINE INJECTION	Panpharma GmbH	SIN03588P	INJECTION	0.5 mg/ml	7/5/1989

NMPA Drug Approvals

Approved Product	Company	Approval Number	Drug Type	Dosage Form	Approval Date
No NMPA approvals found for this drug.

PPB Drug Approvals

Approved Product	Registration No.	Company	Licence No.	Strength	Registration Date
No PPB approvals found for this drug.

TGA Drug Approvals

Approved Product	ARTG ID	Sponsor	Registration Type	Status	Registration Date
SYNTOMETRINE oxytocin / ergometrine maleate 1mL injection ampoule	13396	Phebra Pty Ltd	Medicine	A	8/21/1991
RYMPA INJECTION oxytocin / ergometrine maleate 1mL injection ampoule	162719	Phebra Pty Ltd	Medicine	A	11/8/2010
DBL ERGOMETRINE INJECTION Ergometrine maleate injection	58866	Pfizer Australia Pty Ltd	Medicine	A	3/6/1997

Health Canada Drug Approvals

Approved Product	Company	DIN	Dosage Form	Strength	Market Date
No Health Canada approvals found for this drug.

CIMA AEMPS Drug Approvals

Approved Product	Company	Registration Number	Pharmaceutical Form	Prescription Type	Status
No CIMA AEMPS (Spain) approvals found for this drug.

Philippines FDA Drug Approvals

Approved Product	Company	License Number	Dosage Form	Strength	Approval Date
No Philippines FDA approvals found for this drug.

Saudi SFDA Drug Approvals

Approved Product	Company	License Number	Dosage Form	Strength	Approval Date
No Saudi SFDA approvals found for this drug.

Malaysia NPRA Drug Approvals

Approved Product	Company	Registration Number	Dosage Form	Strength	Approval Date
No Malaysia NPRA approvals found for this drug.

UK EMC Drug Information

Medicine Name	MA Holder	MA Number	Pharmaceutical Form	Active Ingredient	Authorization Date
No UK EMC drug information found for this drug.

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