Calcitriol
- Generic Name
- Calcitriol
- Brand Names
- Rocaltrol, Vectical
- Drug Type
- Small Molecule
- Chemical Formula
- C27H44O3
- CAS Number
- 32222-06-3
- Unique Ingredient Identifier
- FXC9231JVH
- Background
Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D, 1,25-dihydroxyvitamin D. It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to Vitamin D3 (vita...
- Indication
Used to treat vitamin D deficiency or insufficiency, refractory rickets (vitamin D resistant rickets), familial hypophosphatemia and hypoparathyroidism, and in the management of hypocalcemia and renal osteodystrophy in patients with chronic renal failure undergoing dialysis. Also used in conjunction with calcium in the management and prevention of primary or...
- Associated Conditions
- Hypocalcemia, Mild to Moderate Plaque Psoriasis, Osteodystrophy, Secondary Hyperparathyroidism (SHPT), Vitamin D Resistant Rickets
- Associated Therapies
- -
Effect Of Calcitriol On Neutrophil To Lymphocytes Ratio And High Sensitivity C-Reactive Protein Covid-19 Patients
- First Posted Date
- 2023-03-13
- Last Posted Date
- 2023-03-13
- Lead Sponsor
- Universitas Sebelas Maret
- Target Recruit Count
- 16
- Registration Number
- NCT05765617
- Locations
- 🇮🇩
Universitas Sebelas Maret Hospital, Sukoharjo, Central Java, Indonesia
Calcitriol Supplementation in COVID-19 Patients
- First Posted Date
- 2022-06-13
- Last Posted Date
- 2022-06-13
- Lead Sponsor
- RenJi Hospital
- Target Recruit Count
- 86
- Registration Number
- NCT05415254
- Locations
- 🇨🇳
Renji Hospital, Shanghai, Shanghai, China
Comparison of Serum Calcium Level Between Preoperative Vitamin D and Non-vitamin D Regimen of Total Parathyroidectomy in End-stage Renal Failure Patients in Rajavithi Hospital
- Conditions
- Interventions
- First Posted Date
- 2021-07-19
- Last Posted Date
- 2024-01-25
- Lead Sponsor
- Rajavithi Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT04967469
- Locations
- 🇹🇭
Rajavithi Hospital, Bangkok, Thailand
Vitamin D and Cocaine Administration
- First Posted Date
- 2021-04-01
- Last Posted Date
- 2023-08-14
- Lead Sponsor
- Yale University
- Target Recruit Count
- 4
- Registration Number
- NCT04826133
- Locations
- 🇺🇸
Connecticut Mental Health Center, New Haven, Connecticut, United States
Evaluation of the Effects of Calcitriol's in the Neurological Symptoms of Friedreich's Ataxia Patients
- Conditions
- Interventions
- First Posted Date
- 2021-03-17
- Last Posted Date
- 2023-10-23
- Lead Sponsor
- Berta Alemany
- Target Recruit Count
- 20
- Registration Number
- NCT04801303
- Locations
- 🇪🇸
Hospital Santa Caterina/Parc Martí i Julià, Salt, Spain
Bone Markers and Bone Density Changes in Hyperperparathyroid Dialysis Patients Under Cinacalcet Treatment
- Conditions
- Interventions
- First Posted Date
- 2020-11-19
- Last Posted Date
- 2020-11-19
- Lead Sponsor
- Min-Sheng General Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT04637360
- Locations
- 🇨🇳
Min sheng general hospital, Taoyuan city, Taiwan
Vitamin D as a Therapeutic Adjunct in the Stimulant Treatment of ADHD: a Proof-of-concept Tele-health Study of Stimulant-induced Improvement in Neurocognitive Functioning.
- First Posted Date
- 2020-05-13
- Last Posted Date
- 2024-02-07
- Lead Sponsor
- Yale University
- Target Recruit Count
- 3
- Registration Number
- NCT04386811
- Locations
- 🇺🇸
CMHC, New Haven, Connecticut, United States
A Multicenter Randomized Study of Vitamin D Combined With HD-DXM Versus HD-DXM for the Treatment of ITP
- First Posted Date
- 2019-09-19
- Last Posted Date
- 2020-09-09
- Lead Sponsor
- Shandong University
- Target Recruit Count
- 60
- Registration Number
- NCT04094805
- Locations
- 🇨🇳
Qilu hospital, Shandong University, Jinan, Shandong, China
Using Different Doses of Active Vitamin D Combined With Neutral Phosphate in Children With X-linked Hypophosphatemia
- First Posted Date
- 2019-01-29
- Last Posted Date
- 2019-01-30
- Lead Sponsor
- Peking Union Medical College Hospital
- Target Recruit Count
- 100
- Registration Number
- NCT03820518
- Locations
- 🇨🇳
Department of Endocrinology, Peking Union Medical College Hospital, Beijing, Beijing, China
Calcitriol Monotherapy for X-Linked Hypophosphatemia
- Conditions
- Interventions
- First Posted Date
- 2018-11-21
- Last Posted Date
- 2024-03-12
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 20
- Registration Number
- NCT03748966
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Drug Development Updates
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