Calcitriol
- Generic Name
- Calcitriol
- Brand Names
- Rocaltrol, Vectical
- Drug Type
- Small Molecule
- Chemical Formula
- C27H44O3
- CAS Number
- 32222-06-3
- Unique Ingredient Identifier
- FXC9231JVH
- Background
Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D, 1,25-dihydroxyvitamin D. It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to Vitamin D3 (vita...
- Indication
Used to treat vitamin D deficiency or insufficiency, refractory rickets (vitamin D resistant rickets), familial hypophosphatemia and hypoparathyroidism, and in the management of hypocalcemia and renal osteodystrophy in patients with chronic renal failure undergoing dialysis. Also used in conjunction with calcium in the management and prevention of primary or...
- Associated Conditions
- Hypocalcemia, Mild to Moderate Plaque Psoriasis, Osteodystrophy, Secondary Hyperparathyroidism (SHPT), Vitamin D Resistant Rickets
- Associated Therapies
- -
An Intervention to Examine the Effect of Vitamin D on Urine Protein Levels in Type 2 Diabetes
- First Posted Date
- 2017-07-13
- Last Posted Date
- 2018-09-06
- Lead Sponsor
- Hamad Medical Corporation
- Target Recruit Count
- 320
- Registration Number
- NCT03216564
- Locations
- 🇶🇦
Hamad Medical Corporation, Doha, Qatar
Topical Rapamycin and Calcitriol for Angiofibroma of Tuberous Sclerosis
- Conditions
- Interventions
- First Posted Date
- 2017-05-04
- Last Posted Date
- 2017-05-04
- Lead Sponsor
- National Taiwan University Hospital
- Target Recruit Count
- 52
- Registration Number
- NCT03140449
Activated Vitamin D for the Prevention and Treatment of Acute Kidney Injury
- Conditions
- Interventions
- First Posted Date
- 2016-11-11
- Last Posted Date
- 2022-02-03
- Lead Sponsor
- David Leaf
- Target Recruit Count
- 150
- Registration Number
- NCT02962102
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
Safety and Efficacy of Hectorol in Pediatric Patients With Chronic Kidney Disease Stage 3 and 4 With Secondary Hyperparathyroidism Not Yet on Dialysis
- Conditions
- Interventions
- First Posted Date
- 2016-08-09
- Last Posted Date
- 2023-04-27
- Lead Sponsor
- Sanofi
- Target Recruit Count
- 84
- Registration Number
- NCT02859896
- Locations
- 🇺🇸
Investigational Site Number :8400025, Greenville, North Carolina, United States
🇺🇸Investigational Site Number :8400015, Jackson, Mississippi, United States
🇺🇸Investigational Site Number :8400021, Syracuse, New York, United States
Extension Study of CTAP101-CL-3001 or CTAP101-CL-3002
- Conditions
- Interventions
- First Posted Date
- 2014-11-04
- Last Posted Date
- 2016-09-29
- Lead Sponsor
- OPKO Health, Inc.
- Target Recruit Count
- 298
- Registration Number
- NCT02282813
Bone Mass and Strength After Kidney Transplantation
- Conditions
- Interventions
- First Posted Date
- 2014-08-25
- Last Posted Date
- 2022-04-15
- Lead Sponsor
- Columbia University
- Target Recruit Count
- 67
- Registration Number
- NCT02224144
- Locations
- 🇺🇸
Columbia University Irving Medical Center, New York, New York, United States
Long Term Safety and Efficacy Study of Calcitriol 3 mcg/g Ointment in Pediatric Subjects With Plaque Psoriasis
- First Posted Date
- 2014-04-29
- Last Posted Date
- 2021-02-18
- Lead Sponsor
- Galderma R&D
- Target Recruit Count
- 54
- Registration Number
- NCT02125279
- Locations
- 🇺🇸
Johnson Dermatology, Fort Smith, Arkansas, United States
🇺🇸Advanced Skincare Surgery & Medcenter, Burbank, California, United States
🇺🇸University of South Florida, Tampa, Florida, United States
RA-2 13-cis Retinoic Acid (Isotretinoin)
- Conditions
- Interventions
- First Posted Date
- 2014-02-12
- Last Posted Date
- 2021-08-02
- Lead Sponsor
- University of Washington
- Target Recruit Count
- 20
- Registration Number
- NCT02061384
- Locations
- 🇺🇸
University of Washington Medical Center, Seattle, Washington, United States
Safety Study of an Oral Vitamin D Analog in Postmenopausal Women
- Conditions
- Interventions
- First Posted Date
- 2013-10-25
- Last Posted Date
- 2017-07-27
- Lead Sponsor
- Deltanoid Pharmaceuticals
- Registration Number
- NCT01969656
The Effect of Calcitriol on Progress and Activity of Lupus Nephritis
- First Posted Date
- 2013-05-29
- Last Posted Date
- 2013-05-29
- Lead Sponsor
- Guilan University of Medical Sciences
- Target Recruit Count
- 50
- Registration Number
- NCT01863641
- Locations
- 🇮🇷
Razi hospital, Rasht, Guilan, Iran, Islamic Republic of
Drug Development Updates
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