Calcitriol
- Generic Name
- Calcitriol
- Brand Names
- Rocaltrol, Vectical
- Drug Type
- Small Molecule
- Chemical Formula
- C27H44O3
- CAS Number
- 32222-06-3
- Unique Ingredient Identifier
- FXC9231JVH
- Background
Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D, 1,25-dihydroxyvitamin D. It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to Vitamin D3 (vita...
- Indication
Used to treat vitamin D deficiency or insufficiency, refractory rickets (vitamin D resistant rickets), familial hypophosphatemia and hypoparathyroidism, and in the management of hypocalcemia and renal osteodystrophy in patients with chronic renal failure undergoing dialysis. Also used in conjunction with calcium in the management and prevention of primary or...
- Associated Conditions
- Hypocalcemia, Mild to Moderate Plaque Psoriasis, Osteodystrophy, Secondary Hyperparathyroidism (SHPT), Vitamin D Resistant Rickets
- Associated Therapies
- -
Clinical Trial of 0.0003% Calcitriol, 0.1% Tacrolimus, and Petrolatum for the Treatment of Pityriasis Alba
- Conditions
- Interventions
- First Posted Date
- 2011-07-06
- Last Posted Date
- 2012-09-26
- Lead Sponsor
- Universidad Autonoma de San Luis Potosí
- Target Recruit Count
- 39
- Registration Number
- NCT01388517
- Locations
- 🇲🇽
Dermatology Department. Hospital Central "Dr. Ignacio Morones Prieto", San Luis Potosi, Mexico
Vitamin D and Arterial Function in Patients With Chronic Kidney Disease
- Conditions
- Interventions
- First Posted Date
- 2011-06-29
- Last Posted Date
- 2018-09-28
- Lead Sponsor
- University of Colorado, Denver
- Target Recruit Count
- 128
- Registration Number
- NCT01384539
- Locations
- 🇺🇸
University of Colorado Denver Clinical Translational Research Center, Aurora, Colorado, United States
Topical Vitamin D3, Diclofenac or a Combination of Both to Treat Basal Cell Carcinoma
- Conditions
- Interventions
- First Posted Date
- 2011-05-23
- Last Posted Date
- 2015-01-13
- Lead Sponsor
- Maastricht University Medical Center
- Target Recruit Count
- 128
- Registration Number
- NCT01358045
- Locations
- 🇳🇱
Maastricht University Medical Center, Maastricht, Limburg, Netherlands
A Study to Evaluate Alendronate Sodium /Vitamin D3 Combination Tablets(FOSAMAX PLUS) Versus Calcitriol in the Treatment of Osteoporosis in Postmenopausal Women in China (MK-0217A-264)
- Conditions
- Interventions
- First Posted Date
- 2011-05-10
- Last Posted Date
- 2024-06-20
- Lead Sponsor
- Organon and Co
- Target Recruit Count
- 219
- Registration Number
- NCT01350934
Effects of High Dose Calcitriol in Breast Cancer Patients
- First Posted Date
- 2011-02-10
- Last Posted Date
- 2022-04-20
- Lead Sponsor
- University of Rochester
- Target Recruit Count
- 12
- Registration Number
- NCT01293682
- Locations
- 🇺🇸
University of Rochester, Rochester, New York, United States
Paricalcitol Versus Calcitriol for the Management of Renocardiac Syndrome in Renal Transplant Patients
- Conditions
- Interventions
- First Posted Date
- 2010-12-23
- Last Posted Date
- 2015-06-09
- Lead Sponsor
- Ural State Medical University
- Target Recruit Count
- 109
- Registration Number
- NCT01265615
- Locations
- 🇷🇺
Ural Institute of Cardiology, Yekaterinburg, Russian Federation
🇳🇱De Haar Research Foundation, Rotterdam, South Holland, Netherlands
Additive Renoprotective Effects of Oral Calcitriol in IgA Nephropathy Patients Taking Renin-Angiotensin System Blockers
- First Posted Date
- 2010-11-09
- Last Posted Date
- 2016-09-07
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 168
- Registration Number
- NCT01237028
- Locations
- 🇰🇷
Seoul National University Hospital, Seoul, Korea, Republic of
🇰🇷National Health Insurance Corporation Ilsan Hospital, Goyang, Korea, Republic of
🇰🇷CHA University Bundang Medical Center, Seongnam, Korea, Republic of
Study to Evaluate Safety of Vitamin D Receptor Activators in Patients Ages 0 to 16 With Chronic Kidney Disease Stage 5 Receiving Peritoneal Dialysis Within Current Clinical Practice
- Conditions
- Interventions
- First Posted Date
- 2010-06-02
- Last Posted Date
- 2013-08-13
- Lead Sponsor
- AbbVie (prior sponsor, Abbott)
- Target Recruit Count
- 61
- Registration Number
- NCT01134315
- Locations
- 🇺🇸
Site Reference ID/Investigator# 26748, Atlanta, Georgia, United States
🇺🇸Site Reference ID/Investigator# 26769, Boston, Massachusetts, United States
🇺🇸Site Reference ID/Investigator# 26749, Akron, Ohio, United States
Efficacy of Calcitriol in Recent Onset Type 1 Diabetes
- First Posted Date
- 2010-05-10
- Last Posted Date
- 2010-05-10
- Lead Sponsor
- Campus Bio-Medico University
- Registration Number
- NCT01120119
- Locations
- 🇮🇹
Bambino Gesù Children's Hospital, Rome, Italy
🇮🇹Sandro Pertini Hospital, Rome, Italy
🇮🇹University Sapienza, Rome, Italy
Calcitriol in Advanced Intrahepatic Cholangiocarcinoma
- Conditions
- First Posted Date
- 2009-12-24
- Last Posted Date
- 2009-12-24
- Target Recruit Count
- 28
- Registration Number
- NCT01039181
- Locations
- 🇹🇭
Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
Drug Development Updates
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