Magnesium sulfate
- Generic Name
- Magnesium sulfate
- Brand Names
- Concept Ob, Suflave, Suprep Bowel Prep Kit, Tis-U-sol
- Drug Type
- Small Molecule
- Chemical Formula
- MgO4S
- CAS Number
- 7487-88-9
- Unique Ingredient Identifier
- ML30MJ2U7I
- Background
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 1992, p1083)
- Indication
Used for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also used in uterine tetany as a myometriat relaxant.
- Associated Conditions
- Constipation, Convulsions, Hypomagnesemia, Torsades de Pointes, Barium poisoning, Severe Exacerbation of asthma
- Associated Therapies
- Bowel preparation therapy, Soaking aid for minor sprains and bruises
Effectiveness of Calcium Channel Blockade for OP and Carbamate Pesticide Poisoning
- Conditions
- Interventions
- First Posted Date
- 2019-04-23
- Last Posted Date
- 2024-11-25
- Lead Sponsor
- University of Edinburgh
- Target Recruit Count
- 3243
- Registration Number
- NCT03925025
- Locations
- 🇧🇩
Chattogram Medical College Hospital, Chittagong, Bangladesh
🇧🇩Jashore Medical College Hospital, Jessore, Bangladesh
🇧🇩Shaheed Ziaur Rahman Medical College, Bogra, Silimpur, Bangladesh
The Effect of Loading Dose of Magnesium Sulfate on Uterine, Umbilical, and Fetal Middle Cerebral Arteries Doppler, Biophysical Profile, CTG, Maternal Vital Signs in Women With Severe Preeclampsia
- First Posted Date
- 2019-03-27
- Last Posted Date
- 2019-03-27
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 100
- Registration Number
- NCT03891498
- Locations
- 🇪🇬
Kasr Alainy medical school, Cairo, Egypt
Magnesium Sulphate Versus Fentanyl Sedation During Burr-hole Surgery
- Conditions
- Interventions
- First Posted Date
- 2019-02-26
- Last Posted Date
- 2021-04-13
- Lead Sponsor
- Kasr El Aini Hospital
- Target Recruit Count
- 32
- Registration Number
- NCT03854812
- Locations
- 🇪🇬
Kasr Alaini Hospital, Cairo, Egypt
SAP Block to Reduce Post Mastectomy Pain
- Conditions
- Interventions
- First Posted Date
- 2019-01-18
- Last Posted Date
- 2024-04-10
- Lead Sponsor
- Suez Canal University
- Target Recruit Count
- 40
- Registration Number
- NCT03810209
- Locations
- 🇪🇬
Suez Canal University, Ismailia, Egypt
Magnesium Sulfate in the Prevention of Post-ERCP Pancreatitis.
- Conditions
- Interventions
- First Posted Date
- 2018-11-21
- Last Posted Date
- 2021-05-03
- Lead Sponsor
- University Medicine Greifswald
- Target Recruit Count
- 327
- Registration Number
- NCT03749590
- Locations
- 🇩🇪
Klinik für Innere Medizin A, Universitätsmedizin Greifswald, Greifswald, Mecklenburg-Vorpommern, Germany
Comparing Efficacy Preoperative Nebulized: Ketamine , Mgspo4 ,and Lidocaine In Attenuating Endotracheal Sore Throat
- Conditions
- Interventions
- First Posted Date
- 2018-11-05
- Last Posted Date
- 2019-03-19
- Lead Sponsor
- Zagazig University
- Target Recruit Count
- 100
- Registration Number
- NCT03729973
- Locations
- 🇪🇬
Zagazig University Hospitsals, Zagazig, Egypt
Lidocaine Compared to Magnesium Sulfate to Prolong Spinal Anesthesia: Non-inferiority Randomized Clinical Trial
- First Posted Date
- 2018-10-30
- Last Posted Date
- 2020-02-27
- Lead Sponsor
- Brasilia University Hospital
- Target Recruit Count
- 44
- Registration Number
- NCT03725228
- Locations
- 🇧🇷
Hospital Universitário de Brasilia, Brasilia, Distrito Federal, Brazil
Role of Magnesium in Pediatric Cochlear Implant
- First Posted Date
- 2018-10-29
- Last Posted Date
- 2019-10-29
- Lead Sponsor
- Wahba bakhet
- Target Recruit Count
- 66
- Registration Number
- NCT03722940
Intraoperative Magnesium Sulfate Administration During Orthotopic Liver Transplantation
- First Posted Date
- 2018-10-24
- Last Posted Date
- 2020-11-09
- Lead Sponsor
- Fayoum University Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT03717467
- Locations
- 🇪🇬
Sheikh Zayed hospital, Giza, Egypt
Preoperative Oral Magnesium to Prevent Postoperative Atrial Fibrillation Following Coronary Surgery (POMAF-CS)
- Conditions
- Interventions
- First Posted Date
- 2018-10-11
- Last Posted Date
- 2020-04-28
- Lead Sponsor
- St Joseph University, Beirut, Lebanon
- Target Recruit Count
- 200
- Registration Number
- NCT03703349
- Locations
- 🇱🇧
Hotel Dieu de France, Beirut, Lebanon
Drug Development Updates
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