Magnesium sulfate
- Generic Name
- Magnesium sulfate
- Brand Names
- Concept Ob, Suflave, Suprep Bowel Prep Kit, Tis-U-sol
- Drug Type
- Small Molecule
- Chemical Formula
- MgO4S
- CAS Number
- 7487-88-9
- Unique Ingredient Identifier
- ML30MJ2U7I
- Background
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 199...
- Indication
Used for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also ...
- Associated Conditions
- Constipation, Convulsions, Hypomagnesemia, Torsades de Pointes, Barium poisoning, Severe Exacerbation of asthma
- Associated Therapies
- Bowel preparation therapy, Soaking aid for minor sprains and bruises
Magnesium Sulfate to Prevent Brain Injury in Premature Infants
- Conditions
- Locations
- 🇺🇸
Thomas Jefferson University, Philadelphia, Pennsylvania, United States
Field Administration of Stroke Therapy - Magnesium (FAST-MAG) Trial
- Conditions
- Interventions
- First Posted Date
- 2003-04-24
- Last Posted Date
- 2015-08-21
- Lead Sponsor
- Jeffrey L. Saver
- Target Recruit Count
- 1700
- Registration Number
- NCT00059332
- Locations
- 🇺🇸
The Clinical Coordinating Center is: UCLA School of Medicine, 710 Westwood Plaza, Los Angeles, California, United States
Safety and Efficacy of Intravenous Magnesium Sulfate in Modulating Changes in Symptoms and Divalent Cation Levels Associated With Foscavir Therapy: A Phase IV Randomized, Double-Blind, Placebo-Controlled, Cross-Over, Pilot Study
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Astra USA
- Target Recruit Count
- 12
- Registration Number
- NCT00002146
- Locations
- 🇺🇸
Oklahoma City Veterans Administration Med Ctr, Oklahoma City, Oklahoma, United States
Beneficial Effects of Antenatal Magnesium Sulfate (BEAM Trial)
- Conditions
- First Posted Date
- 2001-04-18
- Last Posted Date
- 2019-07-12
- Target Recruit Count
- 2136
- Registration Number
- NCT00014989
- Locations
- 🇺🇸
Case Western University, Cleveland, Ohio, United States
🇺🇸University of Texas Medical Branch - Galveston, Galveston, Texas, United States
🇺🇸MCP Hahnemann University, Philadelphia, Pennsylvania, United States
Study of Magnesium Sulfate in Children With Reduced Bone Density Secondary to Chronic Cholestatic Liver Disease
- Conditions
- First Posted Date
- 2000-12-07
- Last Posted Date
- 2009-01-22
- Lead Sponsor
- National Center for Research Resources (NCRR)
- Target Recruit Count
- 25
- Registration Number
- NCT00007033
- Locations
- 🇺🇸
Children's Hospital Medical Center - Cincinnati, Cincinnati, Ohio, United States
Magnesium Sulfate For Brain Injury
- Conditions
- First Posted Date
- 2000-02-28
- Last Posted Date
- 2011-10-28
- Lead Sponsor
- University of Washington
- Registration Number
- NCT00004730
- Locations
- 🇺🇸
University of Washington, Seattle, Washington, United States
Randomized Study of Nimodipine Versus Magnesium Sulfate in the Prevention of Eclamptic Seizures in Patients With Severe Preeclampsia
- Conditions
- First Posted Date
- 1999-10-19
- Last Posted Date
- 2015-03-25
- Lead Sponsor
- FDA Office of Orphan Products Development
- Target Recruit Count
- 2000
- Registration Number
- NCT00004399
Drug Development Updates
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