Magnesium sulfate
- Generic Name
- Magnesium sulfate
- Brand Names
- Concept Ob, Suflave, Suprep Bowel Prep Kit, Tis-U-sol
- Drug Type
- Small Molecule
- Chemical Formula
- MgO4S
- CAS Number
- 7487-88-9
- Unique Ingredient Identifier
- ML30MJ2U7I
- Background
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 199...
- Indication
Used for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also ...
- Associated Conditions
- Constipation, Convulsions, Hypomagnesemia, Torsades de Pointes, Barium poisoning, Severe Exacerbation of asthma
- Associated Therapies
- Bowel preparation therapy, Soaking aid for minor sprains and bruises
Magnesium Sulphate in Premature Rupture of Membranes
- First Posted Date
- 2021-11-26
- Last Posted Date
- 2024-07-22
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 124
- Registration Number
- NCT05134688
Dexamedtomidine in Control of Intracranial Pressure in Preeclampsia
- Conditions
- Interventions
- First Posted Date
- 2021-11-12
- Last Posted Date
- 2022-02-22
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 100
- Registration Number
- NCT05119101
- Locations
- 🇪🇬
Faculty of medicine Assiut University, Assiut, Egypt
Comparison of MgSO4 Versus Meperidine for Prevention of Shivering During Spinal Anesthesia
- First Posted Date
- 2021-11-08
- Last Posted Date
- 2021-11-08
- Lead Sponsor
- AnestesiaR
- Target Recruit Count
- 100
- Registration Number
- NCT05110469
- Locations
- 🇮🇩
Dr. Cipto Mangunkusumo National General Hospital, Jakarta, DKI Jakarta, Indonesia
Adding Magnesium Sulfate to Bupivacaine in Ultrasound Guided Paravertebral Block for Laparoscopic Cholecystectomy
- Conditions
- Interventions
- First Posted Date
- 2021-10-29
- Last Posted Date
- 2021-11-08
- Lead Sponsor
- Mansoura University
- Target Recruit Count
- 50
- Registration Number
- NCT05099250
- Locations
- 🇪🇬
Marwa Ibrahim Mohamed Abdo, Mansoura, Egypt
Effect of Magnesium Sulfate Bolus on Intraoperative Neuromonitoring
- Conditions
- Interventions
- First Posted Date
- 2021-06-24
- Last Posted Date
- 2024-08-02
- Lead Sponsor
- Loma Linda University
- Target Recruit Count
- 50
- Registration Number
- NCT04938765
- Locations
- 🇺🇸
Loma linda University Medical Center, Loma Linda, California, United States
POPLITEAL SCIATIC NERVE BLOCK FOR DIABETIC FOOT SURGERIES
- First Posted Date
- 2021-05-26
- Last Posted Date
- 2021-05-27
- Lead Sponsor
- Alexandria University
- Target Recruit Count
- 50
- Registration Number
- NCT04903743
- Locations
- 🇪🇬
rehab Abd Elaziz, Alexandria, Egypt
Nebulized Magnesium Sulfate and Sildenafil for Persistent Pulmonary Hypertension of Newborn
- Conditions
- Interventions
- First Posted Date
- 2021-05-24
- Last Posted Date
- 2024-11-27
- Lead Sponsor
- Sohag University
- Target Recruit Count
- 40
- Registration Number
- NCT04898114
- Locations
- 🇪🇬
Neonatal Intensive Care Unit, Sohag University Hospital, Sohag, Egypt
Comparison Between Adjuvants Added to Bupivacaine in Adductor Canal Block
- Conditions
- Interventions
- First Posted Date
- 2021-05-19
- Last Posted Date
- 2022-01-25
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 120
- Registration Number
- NCT04892420
- Locations
- 🇪🇬
Ismail Mohammed Ibrahim, Cairo, Egypt
Magnesium Sulfate for Analgesia in Pediatric Transplant
- First Posted Date
- 2021-03-23
- Last Posted Date
- 2024-10-28
- Lead Sponsor
- University of Minnesota
- Target Recruit Count
- 66
- Registration Number
- NCT04812028
- Locations
- 🇺🇸
University of Minnesota, Minneapolis, Minnesota, United States
Efficacy of Magnesium Sulfate Bolus in Pediatric Patients With Bronchiolitis
- First Posted Date
- 2021-02-05
- Last Posted Date
- 2024-10-10
- Lead Sponsor
- University of Louisville
- Target Recruit Count
- 40
- Registration Number
- NCT04740294
- Locations
- 🇺🇸
Norton Children's Hospital, Louisville, Kentucky, United States
Drug Development Updates
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