Natamycin
- Generic Name
- Natamycin
- Brand Names
- Natacyn
- Drug Type
- Small Molecule
- Chemical Formula
- C33H47NO13
- CAS Number
- 7681-93-8
- Unique Ingredient Identifier
- 8O0C852CPO
- Background
Amphoteric macrolide antifungal antibiotic from Streptomyces natalensis or S. chattanoogensis. It is used for a variety of fungal infections, mainly topically. [PubChem]
- Indication
For the treatment of fungal blepharitis, conjunctivitis, and keratitis caused by susceptible organisms including Fusarium solani keratitis.
- Associated Conditions
- Fungal blepharitis, Fungal conjunctivitis, Fungal infections of the cornea
Trial to Evaluate the Efficacy And Safety of IVIEW-1201 In the Treatment of Fungal Keratitis
- First Posted Date
- 2024-06-18
- Last Posted Date
- 2024-06-18
- Lead Sponsor
- IVIEW Therapeutics Inc.
- Target Recruit Count
- 60
- Registration Number
- NCT06463678
The Antibiogram and Outcomes of Antimicrobial Regimens in Microbial Keratitis: A Prospective Cohort Study
- Conditions
- Mixed Bacterial and Fungal KeratitisFungal KeratitisMicrobial KeratitisBacterial Keratitis
- Interventions
- First Posted Date
- 2022-12-19
- Last Posted Date
- 2024-01-25
- Lead Sponsor
- Alexandria University
- Target Recruit Count
- 123
- Registration Number
- NCT05655689
- Locations
- 🇪🇬
Cornea Outpatient Clinic at Alexandria Main University Hospital, Alexandria, Egypt
Rose Bengal Electromagnetic Activation With Green Light for Infection Reduction
- Conditions
- Acanthamoeba KeratitisFungal Keratitis
- Interventions
- First Posted Date
- 2021-11-05
- Last Posted Date
- 2025-01-31
- Lead Sponsor
- University of California, San Francisco
- Target Recruit Count
- 330
- Registration Number
- NCT05110001
- Locations
- 🇮🇳
Aravind Eye Care System, Madurai, Tamil Nadu, India
🇧🇷Federal University of São Paulo, São Paulo, Brazil
Mycotic Antimicrobial Localized Injection for Treatment of Corneal Ulcers
- Conditions
- Fungal KeratitisCorneal Ulcer
- Interventions
- First Posted Date
- 2016-04-07
- Last Posted Date
- 2019-10-01
- Lead Sponsor
- University of California, San Francisco
- Target Recruit Count
- 70
- Registration Number
- NCT02731638
- Locations
- 🇮🇳
Aravind Eye Hospitals, Pondicherry, Tamil Nadu, India
🇺🇸Francis I. Proctor Foundation at UCSF, San Francisco, California, United States
Mycotic Ulcer Treatment Trial I
- Conditions
- Eye Infections, FungalCorneal Ulcer
- Interventions
- First Posted Date
- 2009-10-16
- Last Posted Date
- 2018-08-01
- Lead Sponsor
- University of California, San Francisco
- Target Recruit Count
- 323
- Registration Number
- NCT00996736
- Locations
- 🇮🇳
Aravind Eye Hospital, Pondicherry, Tamil Nadu, India
🇮🇳Aravind Eye Hospitals, Madurai, Tamil Nadu, India
🇺🇸Proctor Foundation, UCSF, San Francisco, California, United States
Therapeutic Exploratory Study of Comparing Natamycin and Voriconazole to Treat Fungal Corneal Ulcer
- Conditions
- Fungal Keratitis
- Interventions
- First Posted Date
- 2007-11-14
- Last Posted Date
- 2018-08-07
- Lead Sponsor
- University of California, San Francisco
- Target Recruit Count
- 120
- Registration Number
- NCT00557362
- Locations
- 🇮🇳
Aravind Eye Hospital, Pondicherry, Tamil Nadu, India
A Clinical Trial of the Treatment of Fungal Corneal Ulcers With Povidone-Iodine
- Conditions
- Fungal Keratitis
- Interventions
- First Posted Date
- 2007-08-15
- Last Posted Date
- 2014-12-04
- Lead Sponsor
- University of California, Los Angeles
- Target Recruit Count
- 78
- Registration Number
- NCT00516399
Drug Development Updates
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