Theophylline
- Generic Name
- Theophylline
- Brand Names
- Elixophyllin, Elixophylline, Pulmophylline, Quibron-T, Theo-24, Theolair, Uniphyl
- Drug Type
- Small Molecule
- Chemical Formula
- C7H8N4O2
- CAS Number
- 58-55-9
- Unique Ingredient Identifier
- 0I55128JYK
- Background
A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Theophylline is marketed under several brand names such as Uniphyl and Theo...
- Indication
For the treatment of the symptoms and reversible airflow obstruction associated with chronic asthma and other chronic lung diseases, such as emphysema and chronic bronchitis.
- Associated Conditions
- Asthma, Bronchitis, Bronchoconstriction, Bronchospasm, Chronic Obstructive Pulmonary Disease (COPD), Chronic bronchial inflammation
- Associated Therapies
- Airway secretion clearance therapy, Bronchodilation
Effect of Tigulixostat on the Pharmacokinetics of Theophylline
- First Posted Date
- 2024-01-03
- Last Posted Date
- 2024-01-03
- Lead Sponsor
- LG Chem
- Target Recruit Count
- 24
- Registration Number
- NCT06189404
- Locations
- 🇺🇸
PPD - Austin Research Unit, Austin, Texas, United States
Smell in COVID-19 and Efficacy of Nasal Theophylline (SCENT 3)
- First Posted Date
- 2023-07-17
- Last Posted Date
- 2024-07-10
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 41
- Registration Number
- NCT05947643
- Locations
- 🇺🇸
Washington University School of Medicine, Saint Louis, Missouri, United States
Theophylline Treatment for Pseudohypoparathyroidism - Children 2-12 Years Old
- Conditions
- Interventions
- First Posted Date
- 2020-09-16
- Last Posted Date
- 2024-11-01
- Lead Sponsor
- Vanderbilt University Medical Center
- Target Recruit Count
- 34
- Registration Number
- NCT04551170
- Locations
- 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States
Diaphragmatic Ultrasound With Theophylline Therapeutic Trials
- Conditions
- Interventions
- First Posted Date
- 2020-02-13
- Last Posted Date
- 2020-02-13
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 46
- Registration Number
- NCT04269187
Sphenopalatine Blockade Versus Clinical Treatment
- First Posted Date
- 2019-11-04
- Last Posted Date
- 2019-11-04
- Lead Sponsor
- University of Sao Paulo General Hospital
- Target Recruit Count
- 45
- Registration Number
- NCT04148846
- Locations
- 🇧🇷
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Smell Changes & Efficacy of Nasal Theophylline
- Conditions
- Interventions
- First Posted Date
- 2019-06-19
- Last Posted Date
- 2022-03-31
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 27
- Registration Number
- NCT03990766
- Locations
- 🇺🇸
Washington University in St. Louis, Saint Louis, Missouri, United States
The Effect of Doxapram Versus Theophylline on Diaphragmatic Function
- First Posted Date
- 2019-03-28
- Last Posted Date
- 2019-03-28
- Lead Sponsor
- Beni-Suef University
- Target Recruit Count
- 70
- Registration Number
- NCT03894189
- Locations
- 🇪🇬
Beni-Suef University Hospital, Banī Suwayf, Egypt
Theophylline for Low Adenosine Syncope
- First Posted Date
- 2019-01-14
- Last Posted Date
- 2021-01-20
- Target Recruit Count
- 77
- Registration Number
- NCT03803215
- Locations
- 🇮🇹
Department of Cardiology, Ospedali del Tigullio, Lavagna, Italy
Effect of Theophylline in Pseudohypoparathyroidism
- First Posted Date
- 2018-10-24
- Last Posted Date
- 2022-07-22
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 100
- Registration Number
- NCT03718403
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Digital Image Correlation in Right Ventricular Evaluation
- Conditions
- Interventions
- First Posted Date
- 2017-04-14
- Last Posted Date
- 2021-12-08
- Lead Sponsor
- Tampere University Hospital
- Target Recruit Count
- 20
- Registration Number
- NCT03115294
- Locations
- 🇫🇮
Tampere University Hospital, Heart Center, Tampere, Finland
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.