Metyrosine
- Generic Name
- Metyrosine
- Brand Names
- Demser
- Drug Type
- Small Molecule
- Chemical Formula
- C10H13NO3
- CAS Number
- 672-87-7
- Unique Ingredient Identifier
- DOQ0J0TPF7
- Background
An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. (Martindale, The Extra Pharmacopoeia, 30th ed)
- Indication
For use in the treatment of patients with pheochromocytoma, for preoperative preparation of patients for surgery, management of patients when surgery is contraindicated, and chronic treatment of patients with malignant pheochromocytoma.
- Associated Conditions
- Pheochromocytoma
- Associated Therapies
- -
Metyrosine (Demser®) for the Treatment of Psychotic Disorders in Patients With Velocardiofacial Syndrome
Phase 2
Terminated
- Conditions
- Interventions
- First Posted Date
- 2010-05-21
- Last Posted Date
- 2019-11-22
- Lead Sponsor
- Bausch Health Americas, Inc.
- Target Recruit Count
- 2
- Registration Number
- NCT01127503
- Locations
- 🇺🇸
VCFS International Center, Syracuse, New York, United States
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