Desmopressin
- Generic Name
- Desmopressin
- Brand Names
- Ddavp, Nocdurna, Octostim
- Drug Type
- Small Molecule
- Chemical Formula
- C46H64N14O12S2
- CAS Number
- 16679-58-6
- Unique Ingredient Identifier
- ENR1LLB0FP
- Background
Desmopressin (dDAVP), a synthetic analogue of 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1-cysteine and substitution of 8-L-arginine by 8-D-arginine. ADH is an endogenous pituitary hormone that has a crucial role in the control of the water content in the body. Upon release from the stimulation of increased plasm...
- Indication
1.治疗中枢性尿崩症，可减少尿量、提高尿渗透压、降低血浆渗透压；
2.用于尿崩症的诊断和鉴别诊断；
3.用于治疗夜间遗尿症（六岁或以上的患者）；
4.部分类型（甲型血友病和Ⅰ型血管性假血友病）的血友病及其他出血性疾病。
- Associated Conditions
- Bleeding, Hypothalamic Injury-induced Obesity (HIO), Nocturia, Nocturnal Polyuria, Polydipsia, Polyuria, Primary Nocturnal Enuresis
- Associated Therapies
- -
Prevention of Bleeding in Patient With Cirrhosis Undergoing Dental Extraction
- Conditions
- Interventions
- First Posted Date
- 2008-12-31
- Last Posted Date
- 2009-01-01
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Target Recruit Count
- 36
- Registration Number
- NCT00816127
- Locations
- 🇺🇸
Mount Sinai School of Medicine, New York, New York, United States
1-deamino 8-d-arginine Vasopressin (DDAVP) in Percutaneous Ultrasound-guided Renal Biopsy
- First Posted Date
- 2008-09-08
- Last Posted Date
- 2015-01-13
- Lead Sponsor
- University of Bari
- Target Recruit Count
- 162
- Registration Number
- NCT00748072
- Locations
- 🇮🇹
Center and Atelier for Epidemiological Studies, University of Bari, Bari, Italy
Efficacy and Safety of Desmopressin Melt for the Treatment of Nocturia
- First Posted Date
- 2007-05-23
- Last Posted Date
- 2015-11-01
- Lead Sponsor
- Ferring Pharmaceuticals
- Target Recruit Count
- 799
- Registration Number
- NCT00477490
- Locations
- 🇺🇸
PharmQuest, Greensboro, North Carolina, United States
🇺🇸Advanced Research Associates, Corpus Christi, Texas, United States
🇺🇸Accelovance, Houston, Texas, United States
Desmopressin Response in the Young
- First Posted Date
- 2005-10-03
- Last Posted Date
- 2011-05-19
- Lead Sponsor
- Ferring Pharmaceuticals
- Target Recruit Count
- 132
- Registration Number
- NCT00230594
- Locations
- 🇨🇦
The Kids Clinic, Whitby, Ontario, Canada
🇨🇦IWK Health Centre, Halifax, Nova Scotia, Canada
🇨🇦The Male Health Centres, Oakville, Ontario, Canada
Treatment and Management of Women With Bleeding Disorders
- Conditions
- First Posted Date
- 2005-05-19
- Last Posted Date
- 2007-03-13
- Lead Sponsor
- Centers for Disease Control and Prevention
- Target Recruit Count
- 100
- Registration Number
- NCT00111215
- Locations
- 🇺🇸
The Mayo Clinic, Rochester, Minnesota, United States
🇺🇸UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey, United States
🇺🇸Michigan State University, East Lansing, Michigan, United States
Study of Novel Types of Familial Diabetes Insipidus
- Conditions
- First Posted Date
- 1999-10-19
- Last Posted Date
- 2006-02-22
- Lead Sponsor
- National Center for Research Resources (NCRR)
- Target Recruit Count
- 5
- Registration Number
- NCT00004364
Study of the Pathogenesis and Pathophysiology of Familial Neurohypophyseal Diabetes Insipidus
- Conditions
- First Posted Date
- 1999-10-19
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- National Center for Research Resources (NCRR)
- Registration Number
- NCT00004363
- Locations
- 🇺🇸
Northwestern University Medical School, Chicago, Illinois, United States
Drug Development Updates
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