Overview
Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow resistance in the diseased lung, leading to decreased cardiovascular workload in an attempt to oxygenate the lungs. Oxygen therapy is used to treat emphysema, pneumonia, some heart disorders (congestive heart failure), some disorders that cause increased pulmonary artery pressure, and any disease that impairs the body's ability to take up and use gaseous oxygen. Higher level of oxygen than ambient air (hyperoxia) can be introduced under normobaric or hyperbaric conditions.
Background
Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow resistance in the diseased lung, leading to decreased cardiovascular workload in an attempt to oxygenate the lungs. Oxygen therapy is used to treat emphysema, pneumonia, some heart disorders (congestive heart failure), some disorders that cause increased pulmonary artery pressure, and any disease that impairs the body's ability to take up and use gaseous oxygen. Higher level of oxygen than ambient air (hyperoxia) can be introduced under normobaric or hyperbaric conditions.
Indication
Oxygen therapy in clinical settings is used across diverse specialties, including various types of anoxia, hypoxia or dyspnea and any other disease states and conditions that reduce the efficiency of gas exchange and oxygen consumption such as respiratory illnesses, trauma, poisonings and drug overdoses. Oxygen therapy tries to achieve hyperoxia to reduce the extent of hypoxia-induced tissue damage and malfunction.
Associated Conditions
- Anemia
- Cancer
- Hypoxemia
- Hypoxia
- Migraine
- Polycythemia
- Pulmonary Hypertension (PH)
- Respiratory Disorders
- Sleep Apnea
Clinical Trials
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Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2020/05/21 | Phase 2 | Withdrawn | Roger Alvarez | ||
2020/05/07 | Phase 2 | Terminated | |||
2020/03/31 | Phase 2 | Terminated | |||
2020/03/13 | Not Applicable | Recruiting | Dalarna County Council, Sweden | ||
2020/03/09 | Phase 2 | Recruiting | Bernardino Clavo, MD, PhD | ||
2020/03/05 | Phase 4 | Completed | Hyperbaric Center Basel | ||
2020/02/05 | Phase 3 | Recruiting | |||
2020/01/10 | Phase 4 | Recruiting | Esbjerg Hospital - University Hospital of Southern Denmark | ||
2020/01/03 | Phase 3 | Recruiting | |||
2019/12/23 | Phase 2 | Completed |
FDA Drug Approvals
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Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| American Medical Gas LLC | 68419-0001 | RESPIRATORY (INHALATION) | 99 L in 100 L | 1/12/2010 | |
| Nor-Lea Hospital District dba Nor-Lea Home Medical | 75928-001 | RESPIRATORY (INHALATION) | 99 L in 100 L | 2/11/2011 | |
| Virginia Medical and Respiratory Equipment Inc | 60563-001 | RESPIRATORY (INHALATION) | 99 L in 100 L | 12/11/2023 | |
| RTA Homecare, Inc. | 54982-0001 | RESPIRATORY (INHALATION) | 99 L in 100 L | 10/29/2009 | |
| Atlanta Medical Gas LLC | 42165-0001 | RESPIRATORY (INHALATION) | 99 L in 100 L | 1/1/2010 | |
| Wilkinson Pharmacy, Inc. | 24846-0001 | RESPIRATORY (INHALATION) | 99 L in 100 L | 10/29/2009 | |
| T.W. Smith Corp. | 52563-001 | RESPIRATORY (INHALATION) | 99.9 L in 1 L | 10/15/2018 | |
| Apollo Services Inc. | 24781-0001 | RESPIRATORY (INHALATION) | 99 L in 100 L | 10/9/2009 | |
| MID-SOUTH WELDING SUPPLY, INC. | 51400-001 | RESPIRATORY (INHALATION) | 99 L in 100 L | 10/18/2023 | |
| Shaw Oxygen Company Inc | 54767-001 | RESPIRATORY (INHALATION) | 995 mL in 1 L | 10/18/2023 |
EMA Drug Approvals
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Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
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Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
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Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| Oxygen | 国药准字H20045597 | 化学药品 | 液体 | 3/17/2021 | |
| Oxygen | 国药准字H20058620 | 化学药品 | 液态氧 | 3/20/2020 | |
| Oxygen | 国药准字H20083356 | 化学药品 | N/A | 6/14/2023 | |
| Oxygen | 国药准字H20193215 | 化学药品 | 液态 | 7/25/2019 | |
| Oxygen | 国药准字H20074069 | 化学药品 | N/A | 5/9/2022 | |
| Oxygen | 国药准字H20233948 | 化学药品 | 液态 | 7/25/2023 | |
| Oxygen | 国药准字H20073390 | 化学药品 | 氧(液态) | 8/3/2020 | |
| Oxygen | 国药准字H20059932 | 化学药品 | N/A | 7/9/2021 | |
| Oxygen | 国药准字H20073220 | 化学药品 | N/A | 10/12/2021 | |
| Oxygen | 国药准字H20203126 | 化学药品 | 液态 | 3/24/2020 |
PPB Drug Approvals
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Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| No PPB approvals found for this drug. | |||||
TGA Drug Approvals
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Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
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| No TGA approvals found for this drug. | |||||