Oxygen
- Generic Name
- Oxygen
- Brand Names
- Alnox, Ez-OX, Heliox, Oxygen, Southern Medical
- Drug Type
- Small Molecule
- Chemical Formula
- O2
- CAS Number
- 7782-44-7
- Unique Ingredient Identifier
- S88TT14065
- Background
Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow resistance in the diseased lung, leading to decreased cardiovascular workload in an attempt to oxygenate the lungs. Oxygen therapy is used to treat emphysema, pneumonia, some heart disorders (congestive heart failure), some disorders that cause increased pulmonary artery pressure, and any disease that impairs the body's ability to take up and use gaseous oxygen. Higher level of oxygen than ambient air (hyperoxia) can be introduced under normobaric or hyperbaric conditions.
- Indication
Oxygen therapy in clinical settings is used across diverse specialties, including various types of anoxia, hypoxia or dyspnea and any other disease states and conditions that reduce the efficiency of gas exchange and oxygen consumption such as respiratory illnesses, trauma, poisonings and drug overdoses. Oxygen therapy tries to achieve hyperoxia to reduce the extent of hypoxia-induced tissue damage and malfunction.
- Associated Conditions
- Anemia, Cancer, Hypoxemia, Hypoxia, Migraine, Polycythemia, Pulmonary Hypertension (PH), Respiratory Disorders, Sleep Apnea
- Associated Therapies
- -
Benefits of Liquid Oxygen in COPD Patients Presenting Desaturation During Exercise.
- First Posted Date
- 2014-10-24
- Last Posted Date
- 2018-08-07
- Lead Sponsor
- Jtarrega
- Target Recruit Count
- 112
- Registration Number
- NCT02273830
- Locations
- 🇪🇸
Hospital General de Granollers, Granollers, BArcelona, Spain
The Effect of N2O on Chronic Neuropathic Pain Patients
- First Posted Date
- 2014-09-22
- Last Posted Date
- 2014-09-22
- Lead Sponsor
- Tel-Aviv Sourasky Medical Center
- Target Recruit Count
- 20
- Registration Number
- NCT02246517
- Locations
- 🇮🇱
Pain Medicine Unit, Tel Aviv, Israel
Impact of Breathing Maneuvers on the Oxygenation Supply of the Heart Assessed With MRI in Patients With Coronary Artery Disease
- Conditions
- Coronary Artery Disease
- Interventions
- First Posted Date
- 2014-09-08
- Last Posted Date
- 2017-12-15
- Lead Sponsor
- Insel Gruppe AG, University Hospital Bern
- Target Recruit Count
- 36
- Registration Number
- NCT02233634
- Locations
- 🇨🇭
Bern University Hospital, Bern, Switzerland
Effects of Subanesthetic Isoflurane/Sevoflurane in 60% Oxygen on Clinical In-vitro Experimental Sepsis
- First Posted Date
- 2014-07-09
- Last Posted Date
- 2014-07-09
- Lead Sponsor
- Air Force Military Medical University, China
- Target Recruit Count
- 50
- Registration Number
- NCT02185118
- Locations
- 🇨🇳
Department of Anesthesiology, Xijing Hospital, Fourth Military Medical University,, Xi'an, Shaanxi, China
Patients With Pulmonary Hypertension or Interstitial Lung Disease at Altitude - Effect of Oxygen on Breathing and Sleep
- Conditions
- Precapillary Pulmonary HypertensionInterstitial Lung Disease
- Interventions
- Behavioral: Moderate altitude sojournBehavioral: Low altitude sojournDrug: OxygenDrug: Sham oxygen (room air)
- First Posted Date
- 2014-05-30
- Last Posted Date
- 2020-02-06
- Lead Sponsor
- University of Zurich
- Target Recruit Count
- 50
- Registration Number
- NCT02150616
- Locations
- 🇨🇭
University Hospital Zurich, Pulmonary Division, Zurich, Switzerland
Patients With Chronic Obstructive Pulmonary Disease at Altitude - Effect of Nocturnal Oxygen on Breathing and Sleep
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD)
- Interventions
- Drug: OxygenDrug: sham oxygen (room air)
- First Posted Date
- 2014-05-30
- Last Posted Date
- 2019-01-29
- Lead Sponsor
- University of Zurich
- Target Recruit Count
- 32
- Registration Number
- NCT02150590
- Locations
- 🇨🇭
University Hospital Zurich, Pulmonary Division, Zurich, Switzerland
Patients With Chronic Obstructive Pulmonary Disease at Altitude - Effect of Nocturnal Oxygen on Exercise Performance
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD)
- Interventions
- Drug: oxygenDrug: sham oxygen (room air)
- First Posted Date
- 2014-05-21
- Last Posted Date
- 2019-05-14
- Lead Sponsor
- University of Zurich
- Target Recruit Count
- 32
- Registration Number
- NCT02143609
- Locations
- 🇨🇭
University Hospital Zurich, Pulmonary Division, Zurich, Switzerland
Patients With Pulmonary Hypertension or Interstitial Lung Disease at Altitude - Effect of Oxygen on Exercise Performance
- Conditions
- Interstitial Lung DiseasePrecapillary Pulmonary Hypertension
- Interventions
- Behavioral: Moderate altitude sojournBehavioral: Low altitude sojournDrug: OxygenDrug: Sham oxygen (room air)
- First Posted Date
- 2014-05-21
- Last Posted Date
- 2021-10-07
- Lead Sponsor
- University of Zurich
- Target Recruit Count
- 30
- Registration Number
- NCT02143687
- Locations
- 🇨🇭
University Hospital Zurich, Pulmonary Division, Zurich, Switzerland
The Use of Heliox in Obstructive Sleep Apnea Syndrome
- First Posted Date
- 2014-05-12
- Last Posted Date
- 2015-06-01
- Lead Sponsor
- Northwell Health
- Target Recruit Count
- 32
- Registration Number
- NCT02135900
- Locations
- 🇺🇸
Sleep center, Staten Island University Hospital, Staten Island, New York, United States
Effect of Oxygen Supplementation During Exercise in Chronic Obstructive Pulmonary Disease Patients
- Conditions
- HypoxiaChronic Obstructive Pulmonary Disease
- Interventions
- First Posted Date
- 2014-04-09
- Last Posted Date
- 2018-03-23
- Lead Sponsor
- LHL Helse
- Target Recruit Count
- 16
- Registration Number
- NCT02108925
- Locations
- 🇳🇴
LHL-klinikkene Glittre, Hakadal, Akershus, Norway
Drug Development Updates
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