Oxygen

Generic Name
Oxygen
Brand Names
Alnox, Ez-OX, Heliox, Oxygen, Southern Medical
Drug Type
Small Molecule
Chemical Formula
O2
CAS Number
7782-44-7
Unique Ingredient Identifier
S88TT14065
Background

Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow resistance in the diseased lung, leading to decreased cardiovascular workload in an attempt to oxygenate the lungs. Oxygen therapy is used to treat emphysema, pneumonia, some heart disorders (congestive heart failure), some disorders that cause increased pulmonary artery pressure, and any disease that impairs the body's ability to take up and use gaseous oxygen. Higher level of oxygen than ambient air (hyperoxia) can be introduced under normobaric or hyperbaric conditions.

Indication

Oxygen therapy in clinical settings is used across diverse specialties, including various types of anoxia, hypoxia or dyspnea and any other disease states and conditions that reduce the efficiency of gas exchange and oxygen consumption such as respiratory illnesses, trauma, poisonings and drug overdoses. Oxygen therapy tries to achieve hyperoxia to reduce the extent of hypoxia-induced tissue damage and malfunction.

Associated Conditions
Anemia, Cancer, Hypoxemia, Hypoxia, Migraine, Polycythemia, Pulmonary Hypertension (PH), Respiratory Disorders, Sleep Apnea
Associated Therapies
-

Supplemental Oxygen - Effect on Occurrence of Subsequent Cancer After Abdominal Surgery (Follow-up of the PROXI Trial)

Completed
Conditions
Interventions
First Posted Date
2012-11-07
Last Posted Date
2024-11-18
Lead Sponsor
Lars S. Rasmussen
Target Recruit Count
1386
Registration Number
NCT01723280
Locations
🇩🇰

Dept. of Anesthesia, HOC, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark

Ambulatory Oxygen Effects on Muscles in COPD

Phase 4
Completed
Conditions
Interventions
First Posted Date
2012-11-06
Last Posted Date
2014-12-03
Lead Sponsor
University of Birmingham
Target Recruit Count
25
Registration Number
NCT01722370
Locations
🇬🇧

Heart of England NHS Foundation Trust, Birmingham, West Midlands, United Kingdom

Neonatal Cerebral Oxygenation After Exposure to Oxygen Evaluated With the INVOS Oximeter

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2012-09-24
Last Posted Date
2013-11-08
Lead Sponsor
Copenhagen University Hospital, Hvidovre
Target Recruit Count
33
Registration Number
NCT01690650
Locations
🇩🇰

Department of Paediatrics, Copenhagen University Hospital; Hvidovre, Hvidovre, Denmark

A Study Investigating Ways to Make Local Anaesthetic Hand Surgery Less Painful - Reducing Tourniquet Associated Pain

First Posted Date
2012-06-04
Last Posted Date
2015-05-28
Lead Sponsor
University of Oxford
Target Recruit Count
50
Registration Number
NCT01611064
Locations
🇬🇧

John Radcliffe Hospital, Oxford, United Kingdom

Supplemental Oxygen in Catheterized Coronary Emergency Reperfusion

First Posted Date
2011-08-26
Last Posted Date
2016-08-31
Lead Sponsor
Region Skane
Target Recruit Count
100
Registration Number
NCT01423929
Locations
🇸🇪

SUS Lund, Lund, Sweden

🇸🇪

SUS Malmö, Malmö, Sweden

🇸🇪

Helsingborg Hospital, Helsingborg, Sweden

Normal Oxygenation Versus Hyperoxia in the Intensive Care Unit (ICU)

First Posted Date
2011-03-22
Last Posted Date
2011-03-22
Lead Sponsor
University of Modena and Reggio Emilia
Target Recruit Count
660
Registration Number
NCT01319643
Locations
🇮🇹

Terapia Intensiva Post-operatoria. Azienda Ospedaliero Universitaria Policlinico di Modena, Modena, Italy

A Pilot Study of Demand Valve Oxygen Inhalation Therapy for Cluster Headache

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2011-02-18
Last Posted Date
2019-07-11
Lead Sponsor
Geisinger Clinic
Target Recruit Count
4
Registration Number
NCT01298921
Locations
🇺🇸

Geisinger Wyoming Valley, Wilkes-Barre, Pennsylvania, United States

Cardiac Hemodynamics in Overlap Syndrome (COPD With Obstructive Sleep Apnea)

First Posted Date
2010-12-16
Last Posted Date
2017-01-12
Lead Sponsor
Brigham and Women's Hospital
Registration Number
NCT01261377
Locations
🇺🇸

Massachussets General Hospital, Boston, Massachusetts, United States

🇺🇸

Brigham and Women's Hospital, Boston, Massachusetts, United States

Postpartum Oxygen Inhalation for the Treatment of Postpartum Haemorrhage

Phase 4
Conditions
Interventions
First Posted Date
2010-08-12
Last Posted Date
2011-02-14
Lead Sponsor
Erzincan Military Hospital
Target Recruit Count
450
Registration Number
NCT01180192
Locations
🇹🇷

Bakirkoy Women's and Children's Teaching Hospital, Istanbul, Turkey

Phamacological Reversal of Airway Instability During Sedation

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2010-07-28
Last Posted Date
2015-04-27
Lead Sponsor
University of Rochester
Target Recruit Count
10
Registration Number
NCT01171118
Locations
🇺🇸

University of Rochester Medical Center, Rochester, New York, United States

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