MedPath

LB54640

Generic Name
LB54640
Drug Type
Small Molecule
Background

LB54640 is orally-administered small molecule agonist of the melanocortin 4 receptor.

A Study to Assess Efficacy and Safety of LB54640 in Patients With Hypothalamic Obesity

Phase 2
Active, not recruiting
Conditions
Hypothalamic Obesity
Interventions
Drug: Placebo
First Posted Date
2023-09-21
Last Posted Date
2025-03-03
Lead Sponsor
Rhythm Pharmaceuticals, Inc.
Target Recruit Count
28
Registration Number
NCT06046443
Locations
🇺🇸

Children's Hospital Colorado, Aurora, Colorado, United States

🇺🇸

University of Iowa Children's Hospital, Iowa City, Iowa, United States

🇺🇸

Tufts Medical Center, Boston, Massachusetts, United States

and more 7 locations

A Phase 2 Study to Assess Efficacy and Safety of LB54640 in Patients With Genetic Obesity

Phase 2
Not yet recruiting
Conditions
LEPR Deficiency Obesity
POMC Deficiency Obesity
PCSK1 Deficiency Obesity
Interventions
First Posted Date
2023-09-18
Last Posted Date
2023-11-02
Lead Sponsor
LG Chem
Target Recruit Count
4
Registration Number
NCT06041841
Locations
🇫🇷

Pitié Salpêtrière hospital and Sorbonne Université, Paris, France

🇬🇧

Cambridge university, Cambridge, United Kingdom

A First in Human Study to Assess the Safety, Tolerability of LB54640 in in Healthy Overweight and Obese Subjects

Phase 1
Completed
Conditions
Overweight
Healthy
Obese
Interventions
Drug: Placebo
First Posted Date
2023-09-15
Last Posted Date
2023-09-15
Lead Sponsor
LG Chem
Target Recruit Count
112
Registration Number
NCT06040372
Locations
🇺🇸

Clinical Research Unit, Chula Vista, California, United States

© Copyright 2025. All Rights Reserved by MedPath