Tramadol
- Generic Name
- Tramadol
- Brand Names
- Conzip, Durela, Qdolo, Ralivia, Ryzolt, Seglentis, Tridural, Ultracet, Ultram, Zytram
- Drug Type
- Small Molecule
- Chemical Formula
- C16H25NO2
- CAS Number
- 27203-92-5
- Unique Ingredient Identifier
- 39J1LGJ30J
- Background
Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. It is consider...
- Indication
Tramadol is approved for the management of moderate to severe pain in adults.
Tramadol is also used off-label in the treatment of premature ejaculation.
- Associated Conditions
- Acute Pain, Premature Ejaculation, Severe Pain, Acute, moderate, severe Pain, Moderate Pain
- Associated Therapies
- -
Method of Pre-treatment for Application of QUTENZA Capsaicin 8% Patch
- Conditions
- Interventions
- First Posted Date
- 2011-08-12
- Last Posted Date
- 2018-04-23
- Lead Sponsor
- Astellas Pharma Inc
- Target Recruit Count
- 122
- Registration Number
- NCT01416116
- Locations
- 🇧🇪
Site 102, Antwerpen, Belgium
🇧🇪Site 103, Genk, Belgium
🇧🇪Site 101, Roeselare, Belgium
Analgesic Effect of Different Combinations of Dexketoprofen Trometamol With Tramadol Hydrochloride in a Model of Moderate to Severe Pain
- Conditions
- Interventions
- First Posted Date
- 2011-03-02
- Last Posted Date
- 2013-08-12
- Lead Sponsor
- Menarini Group
- Target Recruit Count
- 745
- Registration Number
- NCT01307020
- Locations
- 🇩🇪
Klinik für Mund-, Kiefer- und Gesichtschirurgie, Universitätsklinikum Schleswig Holstein, Campus Kiel, Kiel, Schleswig-Holstein, Germany
🇮🇹Centro di Ricerche Cliniche di Verona Srl. Policlinico G.B.Rossi, Verona, Italy
🇬🇧University Dental School Manchester, Manchester, England, United Kingdom
Patient Preferences, Analgesic Delivery Method and Pain Reduction in Spine Patients
- Conditions
- Interventions
- First Posted Date
- 2010-12-21
- Last Posted Date
- 2020-05-27
- Lead Sponsor
- Western Galilee Hospital-Nahariya
- Registration Number
- NCT01263652
The Effects of Three Oral Medications on Post-operative Pain Following Endodontic Treatment
- Conditions
- First Posted Date
- 2010-08-10
- Last Posted Date
- 2010-08-10
- Lead Sponsor
- Azad University of Medical Sciences
- Registration Number
- NCT01178203
Efficacy, Safety, Tolerability and Pharmacokinetics of Concomitant Administration of Tramadol With Duloxetine or Pregabalin
- Conditions
- Interventions
- First Posted Date
- 2010-05-05
- Last Posted Date
- 2013-05-31
- Lead Sponsor
- Turku University Hospital
- Registration Number
- NCT01116531
- Locations
- 🇫🇮
Department of Anaesthesiology, Intensive Care, Emergency Care and Pain Medicine, Turku University and Turku University Hospital, Turku, Finland
Study to Evaluate Efficacy and Safety in Male Subjects With Premature Ejaculation
- Conditions
- Interventions
- First Posted Date
- 2009-09-24
- Last Posted Date
- 2012-08-27
- Lead Sponsor
- Bausch Health Americas, Inc.
- Target Recruit Count
- 1050
- Registration Number
- NCT00983736
- Locations
- 🇧🇬
MHAT Plovdiv, Plovdiv, Bulgaria
🇷🇴Spitalul Clinic de Urgenta Militar Central "Dr. Carol Davila", Bucuresti, Romania
🇨🇿Psychiatricke Oddeienf and Sexuologicka Ambulance, Pardubice, Czech Republic
Development of Cocktail for Measuring the Activity of Important Cytochrome P450 Enzymes
- Conditions
- Interventions
- First Posted Date
- 2009-09-22
- Last Posted Date
- 2010-06-28
- Lead Sponsor
- University of Southern Denmark
- Target Recruit Count
- 412
- Registration Number
- NCT00981929
- Locations
- 🇩🇰
University of Southern Denmark, Clinical Pharmacology, Odense, Fyn, Denmark
Efficacy of Extended Release Tramadol for Treating Prescription Opioid Withdrawal
- First Posted Date
- 2009-09-18
- Last Posted Date
- 2017-04-05
- Lead Sponsor
- Michelle Lofwall
- Target Recruit Count
- 53
- Registration Number
- NCT00980044
- Locations
- 🇺🇸
University of Kentucky, Lexington, Kentucky, United States
Comparative Bioavailability Between Two Tramadol Formulations: Study of the Better Controlled Release of a New 200 mg Once A Day (OAD) Formulation Versus Zytram® 200 mg
- First Posted Date
- 2009-06-02
- Last Posted Date
- 2012-04-27
- Lead Sponsor
- Labopharm Inc.
- Target Recruit Count
- 26
- Registration Number
- NCT00911742
A Study to Compare the Relative Bioavailability of Two 200 Mg Tramadol Hydrochloride Tablet Products Under Fasting Conditions
- First Posted Date
- 2009-02-03
- Last Posted Date
- 2012-04-30
- Lead Sponsor
- Labopharm Inc.
- Target Recruit Count
- 26
- Registration Number
- NCT00834366
Drug Development Updates
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