MedPath

Tofacitinib

Generic Name
Tofacitinib
Brand Names
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Indication

⑴临床用于对甲氨蝶呤疗效不足或对其无法耐受的中度至重度活动性类风湿关节炎成年患者的治疗,可与甲氨蝶呤或其他非生物改善病情抗风湿药(DMARD)联合使用。

⑵用于治疗溃疡性结肠炎(UC)【美国FDA已批准】。

⑶用于成人活动性银屑病关节炎(PsA)(传统改善病情抗风湿药和其他生物改善病情抗风湿药疗效不足或不耐受)【1.美国FDA批准托法替布用于活动性银屑病关节炎;2.《中国关节病型银屑病诊疗共识》(2020);3.美国风湿病学会ACR/NPF《银屑病关节炎的治疗》(2018)】。

⑷用于≥2岁人群活动性多关节病程的幼年特发性关节炎(pcJIA)【美国FDA已批准】。

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