Cetirizine

Generic Name: Cetirizine

Brand Names: Aller-tec, Aller-tec D, Quzyttir, Reactine, Wal Zyr 24 Hour Allergy, Wal Zyr D, Wal-zyr, Zerviate, Zyrtec, Zyrtec-D

Drug Type: Small Molecule

Chemical Formula: C_₂₁H_₂₅ClN_₂O_₃

CAS Number: 83881-51-0

Unique Ingredient Identifier: YO7261ME24

Background: Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms , .
...

Indication: Seasonal Allergic Rhinitis: Indicated for the relief of symptoms associated with seasonal allergic rhinitis caused by allergens such as ragweed, grass and tree pollens in adults and children 2 years of age and above. Symptoms treated effectively include sneezing, rhinorrhea, nasal pruritus, ocular pruritus, tearing, and redness of the eyes .
...

Associated Conditions: Allergy to Tree Pollen, Chronic Idiopathic Urticaria, Flu caused by Influenza, Perennial Allergic Rhinitis (PAR), Respiratory Allergy, Seasonal Allergic Rhinitis

Associated Therapies: -

Clinical Trials

Pharmacokinetic Study of Levocetirizine Oral Solution

Phase 1

Completed

Conditions: Rhinitis, Allergic, Perennial and Seasonal

Interventions: Drug: Cetirizine
Drug: Levocetirizine

First Posted Date: 2012-06-19

Last Posted Date: 2017-06-12

Lead Sponsor: GlaxoSmithKline

Target Recruit Count: 20

Registration Number: NCT01622283

Locations: 🇯🇵
GSK Investigational Site, Kagoshima, Japan

Efficacy, Safety, and Tolerability Study of ACT-129968 in Patients With Seasonal Allergic Rhinitis

Phase 3

Completed

Conditions: Seasonal Allergic Rhinitis

Interventions: Drug: Placebo
Drug: ACT-129968
Drug: Cetirizine

First Posted Date: 2011-12-02

Last Posted Date: 2018-09-28

Lead Sponsor: Idorsia Pharmaceuticals Ltd.

Target Recruit Count: 630

Registration Number: NCT01484119

Locations: 🇺🇸
Clinical Investigative Site 7903, New Braunfels, Texas, United States
🇺🇸
Clinical Investigative Site 7905, Austin, Texas, United States
🇺🇸
Clinical Investigative Site 7901, San Antonio, Texas, United States

and more 4 locations

To Test Bioequivalence Between Two Tablet Formulations in the Treatment of Allergy

Phase 1

Completed

Conditions: Allergy

Interventions: Drug: Cetirizine

First Posted Date: 2011-03-24

Last Posted Date: 2012-07-10

Lead Sponsor: McNeil AB

Target Recruit Count: 36

Registration Number: NCT01322282

Locations: 🇨🇦
Algorithme Pharma Inc., Mount-Royal, Quebec, Canada

Study of ACT-129968 in Adult Patients With Seasonal Allergic Rhinitis

Phase 2

Completed

Conditions: Seasonal Allergic Rhinitis

Interventions: Drug: ACT-129968
Drug: Cetirizine
Drug: Placebo

First Posted Date: 2010-11-16

Last Posted Date: 2019-05-15

Lead Sponsor: Idorsia Pharmaceuticals Ltd.

Target Recruit Count: 579

Registration Number: NCT01241214

Locations: 🇺🇸
Clinical Investigative Site 7902, San Antonio, Texas, United States
🇺🇸
Clinical Investigative Site 7901, San Antonio, Texas, United States
🇺🇸
Clinical Investigative Site 7906, San Antonio, Texas, United States

and more 4 locations

Efficacy Study for the Symptomatic Treatment of Perennial Allergic Rhinitis With a 1 Year Safety Extension

Phase 3

Completed

Conditions: Perennial Allergic Rhinitis

Interventions: Drug: Placebo
Drug: Bilastine
Drug: Cetirizine

First Posted Date: 2010-05-21

Last Posted Date: 2012-09-26

Lead Sponsor: Faes Farma, S.A.

Target Recruit Count: 650

Registration Number: NCT01127620

Cetirizine Hydrochloride Tablets, 10 mg Bioequivalence Study of Dr.Reddy's Under Fed Condition

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: Cetirizine Hydrochloride

First Posted Date: 2010-02-08

Last Posted Date: 2010-02-08

Lead Sponsor: Dr. Reddy's Laboratories Limited

Target Recruit Count: 30

Registration Number: NCT01064115

Cetirizine Hydrochloride Tablets, 10 mg Bioequivalence Study of Dr.Reddy's Under Fasting Condition

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: Cetirizine Hydrochloride

First Posted Date: 2010-02-08

Last Posted Date: 2010-02-08

Lead Sponsor: Dr. Reddy's Laboratories Limited

Target Recruit Count: 30

Registration Number: NCT01064102

Is Levocetirizine Less Sedating Than Cetirizine?

Phase 4

Completed

Conditions: Allergic Rhinitis

Interventions: Drug: Levocetirizine
Drug: Cetirizine
Drug: Placebo

First Posted Date: 2009-01-22

Last Posted Date: 2014-02-20

Lead Sponsor: Vanderbilt University

Target Recruit Count: 30

Registration Number: NCT00826943

Locations: 🇺🇸
Vanderbilt University Asthma, Sinus, and Allergy Clinic, Nashville, Tennessee, United States

A Comparative Double-blind, Double-dummy Study of Desloratadine (DL) 5 mg Once Daily, Cetirizine 10 mg Once Daily, and Placebo Once Daily in Patients With Chronic Idiopathic Urticaria (Study P03736)

Phase 4

Terminated

Conditions: Urticaria

Interventions: Drug: Desloratadine
Drug: Cetirizine
Drug: placebo

First Posted Date: 2008-09-11

Last Posted Date: 2024-08-15

Lead Sponsor: Organon and Co

Target Recruit Count: 149

Registration Number: NCT00751166

A Comparative Double-Blind, Double- Dummy Study of Desloratadine (DL) 5 MG Once Daily, Cetirizine 10 MG Once Daily, and Placebo Once Daily in Patients With Chronic Idiopathic Urticaria (Study P03735)

Phase 4

Completed

Conditions: Urticaria

Interventions: Drug: placebo
Drug: cetirizine
Drug: desloratadine

First Posted Date: 2008-09-11

Last Posted Date: 2024-08-15

Lead Sponsor: Organon and Co

Target Recruit Count: 174

Registration Number: NCT00751218

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.

© Copyright 2024. All Rights Reserved by MedPath

Home Terms & Conditions Privacy Policy