Buprenorphine
- Generic Name
- Buprenorphine
- Brand Names
- Belbuca, Brixadi, Buprenex, Buprenorphine, Butrans, Sublocade, Suboxone, Subutex, Zubsolv, Buvidal, Sixmo
- Drug Type
- Small Molecule
- Chemical Formula
- C29H41NO4
- CAS Number
- 52485-79-7
- Unique Ingredient Identifier
- 40D3SCR4GZ
- Background
Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain. It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is formulated in a 4:1 fixed-dose c...
- Indication
Buprenorphine is available in different formulations, such as sublingual tablets, buccal films, transdermal films, and injections, alone or in combination with naloxone.
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- Associated Conditions
- Opioid Dependence, Severe Pain, Moderate Opioid Dependence, Moderate Pain, Severe Opioid Dependence
- Associated Therapies
- -
The Safety of Using Buprenorphine With Naloxone in a Buccal Film to Initiate Treatment of Opioid Dependent Subjects
- Conditions
- Interventions
- First Posted Date
- 2015-08-05
- Last Posted Date
- 2017-05-04
- Lead Sponsor
- BioDelivery Sciences International
- Registration Number
- NCT02516436
Postoperative Analgesia With Buprenorphine for Postoperative Pain Control and Quality of Life After Spinal Surgery
- Conditions
- Interventions
- First Posted Date
- 2015-04-15
- Last Posted Date
- 2017-05-03
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 69
- Registration Number
- NCT02416804
- Locations
- 🇰🇷
Seoul National University Bundang Hospital, Seongnam, Gyeonggi-do, Korea, Republic of
A Study of the Abuse Liability Potential of ALKS 5461 in Healthy, Non-Dependent, Recreational Opioid Users
- First Posted Date
- 2015-04-09
- Last Posted Date
- 2015-11-10
- Lead Sponsor
- Alkermes, Inc.
- Target Recruit Count
- 56
- Registration Number
- NCT02413281
- Locations
- 🇺🇸
Alkermes Investigational Site, Overland Park, Kansas, United States
Study of the Treatment of Experimental Pain in Buprenorphine Maintained Persons With Chronic Musculoskeletal Pain
- Conditions
- Interventions
- First Posted Date
- 2015-02-26
- Last Posted Date
- 2017-09-11
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 14
- Registration Number
- NCT02372591
- Locations
- 🇺🇸
Behavioral Pharmacology Research Unit, Baltimore, Maryland, United States
Bioequivalence and Adhesion Comparison of Buprenorphine Patches
- First Posted Date
- 2014-10-20
- Last Posted Date
- 2016-02-09
- Lead Sponsor
- Mundipharma Research Limited
- Target Recruit Count
- 104
- Registration Number
- NCT02268422
Efficacy of Pain Treatment on Depression in Patients With Dementia
- Conditions
- Interventions
- First Posted Date
- 2014-10-17
- Last Posted Date
- 2017-04-04
- Lead Sponsor
- University of Bergen
- Target Recruit Count
- 163
- Registration Number
- NCT02267057
- Locations
- 🇳🇴
University of Bergen, Bergen, Norway
Incomplete Response in Late-Life Depression: Getting to Remission With Buprenorphine
- Conditions
- Interventions
- First Posted Date
- 2014-10-13
- Last Posted Date
- 2018-07-26
- Lead Sponsor
- Centre for Addiction and Mental Health
- Target Recruit Count
- 56
- Registration Number
- NCT02263248
- Locations
- 🇨🇦
Centre for Addiction and Mental Health, Toronto, Ontario, Canada
Prolonged Popliteal Fossa Nerve Blockade (Prolonged Pop)
- First Posted Date
- 2014-07-23
- Last Posted Date
- 2017-06-15
- Lead Sponsor
- Hospital for Special Surgery, New York
- Target Recruit Count
- 90
- Registration Number
- NCT02198235
- Locations
- 🇺🇸
Hospital For Special Surgery, New York, New York, United States
Buprenorphine Treatment for Opioid Dependence
- First Posted Date
- 2014-07-10
- Last Posted Date
- 2023-03-10
- Lead Sponsor
- Yale University
- Target Recruit Count
- 9
- Registration Number
- NCT02187198
- Locations
- 🇺🇸
VA Connecticut Healthcare System - West Haven Campus, West Haven, Connecticut, United States
Buprenorphine Used With Treatment Resistant Depression in Older Adults
- Conditions
- Interventions
- First Posted Date
- 2014-07-03
- Last Posted Date
- 2019-06-04
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 18
- Registration Number
- NCT02181231
- Locations
- 🇺🇸
Washington University School of Medicine, Saint Louis, Missouri, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.